Ciflodex 0.3%+0.1% (Ophthalmic Solution)

5 ml drop: ৳ 75.00

Medicine Details

Title and Categories

  • Sterile Eye & Ear Drops
  • Ophthalmic Medication
  • Auricular Medication
  • Steroid and Antibiotic Combination
  • Prescription Medication

Dimensions

Dropper bottle: 5ml

Color Options

  • Transparent bottle
  • Clear liquid

Functions

  • Treats steroid responsive inflammatory ocular conditions with bacterial infections or risk of bacterial infections
  • Treats post-operative inflammation in the eye
  • Treats ear infections accompanied by inflammation
  • Has anti-inflammatory and anti-allergic action
  • Reduces prostaglandin synthesis
  • Inhibits chemotactic infiltration of neutrophils into the site of inflammation
  • Possesses antibacterial activity against a wide range of gram-negative and gram-positive organisms
  • Interferes with the enzyme DNA gyrase for bacterial DNA synthesis

Materials

  • Glass dropper bottle
  • Sterile solution containing Dexamethasone and Ciprofloxacin

Technical Specifications

  • Topically used in the treatment of inflammatory conditions of the anterior segment of the eye
  • Recommended dosage: 1 drop every four to six hours for the eye
  • Dosage for ear infections: 4 drops instilled into the affected ear 2 times daily for 7 days in different ear infection scenarios
  • For pediatric use, safety and effectiveness below 1 year have not been established
  • Storage period after first opening: 30 days

Design Elements

  • Cool and dry storage
  • Child-resistant cap
  • Requires shaking well before each use
  • Sterile formulation

Usability Features

  • Indicated for both eye and ear use
  • Caution exercised in use during pregnancy and lactation
  • Routinely monitor intraocular pressure during prolonged use
  • Avoid use in hypersensitivity to any ingredient of the product, herpes simplex and other viral conditions, mycosis, glaucoma, newborn babies, and fungal diseases of ocular or auricular structures

Side Effects

  • Transient ocular burning or discomfort
  • Stinging, redness, itching, conjunctivitis/keratitis
  • Periocular/facial edema, foreign body sensation, photophobia
  • Blurred vision, tearing, dryness, and eye pain
  • Dizziness
  • Elevation of intraocular pressure (IOP) with possible development of glaucoma
  • Infrequent optic nerve damage, posterior subcapsular cataract formation, delayed wound healing
  • Discomfort and ear pain
  • Irritability, erythema

Interaction

  • Specific drug interaction studies not conducted with ophthalmic Ciprofloxacin and Dexamethasone
  • Systemic administration of some quinolones shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, enhance the effects of the oral anticoagulant warfarin and its derivatives, transient elevations in serum creatinine in patients receiving cyclosporin concomitantly

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution advised for usage during pregnancy if potential benefit justifies potential risk to the fetus
  • Not known whether the drug is excreted in human milk, caution advised during nursing

Precautions & Warnings

  • Consider possibility of fungal infections of the cornea after long-term steroid dosing and in patients with persistent corneal ulceration
  • Prolonged use of antibiotic may result in overgrowth of non-susceptible organisms
  • Prolonged use of topical ophthalmic steroids may result in glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision, posterior subcapsular cataract formation
  • Intraocular pressure should be routinely monitored

Therapeutic Class

Aural steroid & antibiotic combined preparations

Storage Conditions

  • Store in a cool and dry place, away from light
  • Keep out of reach of children
  • Bottle to be closed strongly immediately after use

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