Cipro-D 0.3%+0.1% (Ophthalmic Solution)

5 ml drop: ৳ 75.22

Medicine Details

Category Details
Generic Ciprofloxacin dexamethasone
Company Acme laboratories ltd

Title and Categories

  • Sterile Eye & Ear Drops
  • Ophthalmic and Otic Preparation
  • Steroid and Antibiotic Combination

Color options

  • Clear solution

Dimensions

  • Standard eye drop bottle size

Functions

  • Treatment of steroid responsive inflammatory ocular conditions
  • Treatment of ear infections accompanied by inflammation
  • Post-operative inflammation treatment
  • Anti-inflammatory action
  • Anti-allergic action
  • Topical treatment of anterior segment of the eye
  • Interference with the enzyme DNA gyrase for bacterial DNA synthesis

Materials

  • Dexamethasone
  • Ciprofloxacin

Technical specifications

  • Glucocorticoid
  • Bactericidal action against gram-negative and gram-positive organisms

Design elements

  • Sterile preparation
  • Topical application bottle

Usability features

  • Easy to instill into conjunctival sac(s)
  • Shake well before use
  • To be used within 30 days after first opening
  • Bottle closing mechanism for repeated use

Indications

  • Treatment of steroid responsive inflammatory ocular conditions with bacterial infections or risk of bacterial infections
  • Post-operative inflammation
  • Ear infections with inflammation
  • Otitis externa
  • Acute and chronic otitis media

Dosage and Administration

  • 1 drop to be instilled into conjunctival sac(s) every 4 to 6 hours
  • Dosage increase during initial 24 to 48 hours
  • Different dosages for acute otitis media and otitis externa in pediatric patients with typanastomy tube
  • Pediatric use below 1 year not established

Interaction

  • No specific drug interaction studies conducted with ophthalmic Ciprofloxacin and Dexamethasone
  • Possible elevation of plasma concentrations of theophylline with systemic quinolones
  • Interference with the metabolism of caffeine
  • Enhanced effects of oral anticoagulant warfarin and its derivatives
  • Transient elevations in serum creatinine with cyclosporin concomitantly

Contraindications

  • Hypersensitivity to any ingredient
  • Herpes simplex and other viral conditions
  • Mycosis
  • Glaucoma
  • Newborn babies
  • Fungal diseases of ocular or auricular structures

Side Effects

  • Transient ocular burning or discomfort
  • Stinging
  • Redness
  • Itching
  • Conjunctivitis/Keratitis
  • Periocular/Facial edema
  • Foreign body sensation
  • Photophobia
  • Blurred vision
  • Tearing
  • Dryness
  • Eye pain
  • Dizziness
  • Elevation of intraocular pressure with possible development of glaucoma
  • Optic nerve damage
  • Posterior subcapsular cataract formation
  • Delayed wound healing
  • Discomfort and ear pain
  • Irritability
  • Erythema

Pregnancy & Lactation

  • Use during pregnancy only if potential benefit justifies potential risk to the fetus
  • Caution when used by nursing mothers

Precautions & Warnings

  • Consideration of fungal infections after long-term steroid dosing
  • Monitoring for fungal infections of the cornea
  • Monitoring for overgrowth of non-susceptible organisms with prolonged antibiotic use
  • Monitoring for glaucoma, optic nerve damage, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation with prolonged use of topical ophthalmic steroids
  • Routine monitoring of intraocular pressure

Therapeutic Class

  • Aural steroid & antibiotic combined preparations

Storage Conditions

  • Cool and dry place away from light
  • Keep out of reach of children
  • Shake well before each use
  • Use within 30 days after first opening
  • Strong bottle closure immediately after use

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