Esogut 10 mg (Tablet)

Unit Price: ৳ 3.50 (10 x 10: ৳ 350.00)
Strip Price: ৳ 35.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Biopharma limited
Also available as
Esogut 5 mg suspension Esogut 5 mg pediatric drop

Title

Esogut 10 mg Tablet

Categories

  • Medicine
  • Pharmacology
  • Gastroenterology

Description

Esogut 10 mg Tablet is a dopamine antagonist medication used to treat nausea, vomiting, dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and to speed barium transit in follow-through radiological studies.

Size

10 mg

DosageForm

Tablet

DosageInstructions

    • Adults: 10-20 mg (1-2 tablets), every 6-8 hours daily
    • Children: 0.2-0.4 mg/kg body weight, every 6-8 hours daily
    • Administration: 15-30 minutes before meals and, if necessary, before retiring

MaximumDose

80 mg daily

Contraindications

  • Hypersensitivity to the drug
  • Neonates
  • Gastrointestinal hemorrhage
  • Mechanical obstruction or perforation
  • Prolactin releasing pituitary tumor (prolactinoma)

StorageConditions

Below 30°C, Protected from light & moisture

TherapeuticClass

Motility Stimulants, Motility stimulants/Dopamine antagonist, Prokinetic drugs

ChemicalStructure

  • MolecularFormula: C22H24ClN5O2
  • ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

PregnancyLactation

  • UseInPregnancy: First trimester justified by anticipated therapeutic benefit
  • UseInLactation: Not recommended unless expected benefits outweigh potential risk

Precautions

  • Caution in children due to risk of extra-pyramidal reactions
  • Caution in patients with hepatic impairment

SpecialPopulations

  • UseInInfants: Only with caution and close medical supervision
  • UseInLiverDisorders: With caution due to high hepatic metabolism
  • UseInKidneyDisorders: Dosing frequency may need to be reduced in severe renal insufficiency

Interaction

  • AntagonisticDrugs: Anticholinergic drugs
  • AvoidSimultaneousUseWith:
    • Antacids
    • Antisecretory drugs
    • CYP3A4 inhibitors (e.g., azole antifungals, macrolide antibiotics, HIV protease inhibitors)
  • InfluenceOnAbsorption: May influence absorption of concomitantly orally administered drugs

SideEffects

  • Transient intestinal cramps
  • Rare extrapyramidal phenomena (reverse upon stopping treatment)
  • Increase in plasma prolactin level
  • Rare allergic reactions like rash and urticaria

OverdoseEffects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions

CommonQuestions

  • What is Esogut 10 mg Tablet used for?
  • Quick Tips for usage

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