Quidex 0.3%+0.1% (Ophthalmic Solution)

5 ml drop: ৳ 75.22

Medicine Details

Category Details
Generic Ciprofloxacin dexamethasone
Company Navana pharmaceuticals ltd

Title

  • Sterile Eye & Ear Drops

Categories

  • Medicine
  • Health & Wellness

Description

  • A combination of Dexamethasone, a glucocorticoid with anti-inflammatory and anti-allergic action, and Ciprofloxacin, with broad-spectrum antibacterial activity.

Indications

  • Treatment of steroid responsive inflammatory ocular conditions with co-existing bacterial infections
  • Post-operative inflammation in the eyes
  • Ear infections accompanied by inflammation such as otitis externa and otitis media

Pharmacology

  • Dexamethasone reduces prostaglandin synthesis and inhibits chemotactic infiltration of neutrophils
  • Ciprofloxacin interferes with the enzyme DNA gyrase needed for bacterial DNA synthesis

Dosage & Administration

  • For Eye: instill 1 drop into conjunctival sac(s) every 4-6 hours, may be increased to 1 drop every 2 hours initially
  • For Ear: 4 drops instilled into the affected ear 2 times daily for 7 days

Interaction

  • No specific drug interaction studies conducted with ophthalmic Ciprofloxacin and Dexamethasone
  • Systemic quinolones shown to elevate plasma concentrations of theophylline, interfere with caffeine metabolism, enhance effects of oral anticoagulants, and transiently elevate serum creatinine with cyclosporin concomitantly

Contraindications

  • Hypersensitivity to any ingredient of the product
  • Herpes simplex and other viral conditions
  • Mycosis, glaucoma, newborn babies
  • Fungal diseases of ocular or auricular structures

Side Effects

  • Transient ocular burning, stinging, redness, itching, conjunctivitis, periocular edema, photophobia, blurred vision, elevation of intraocular pressure, optic nerve damage, cataract formation, delayed wound healing, dizziness, discomfort, ear pain, irritability

Pregnancy & Lactation

  • Use during pregnancy only if potential benefit justifies potential risk to the fetus
  • Caution advised when used by nursing mothers due to unknown excretion in human milk

Precautions & Warnings

  • Consider fungal infections of the cornea after long-term steroid dosing
  • Monitor intraocular pressure routinely during prolonged use
  • Potential overgrowth of non-susceptible organisms with prolonged antibiotic use

Therapeutic Class

  • Aural steroid & antibiotic combined preparations

Storage Conditions

  • Store in cool, dry place away from light
  • Keep out of reach of children
  • Shake well before each use
  • Use within 30 days after first opening
  • Close bottle tightly immediately after use

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