Texa 0.1%+0.3% (Ophthalmic Solution)

5 ml drop: ৳ 150.00

Medicine Details

Category Details
Generic Dexamethasone tobramycin
Company Drug international ltd

Indications

  • Steroid responsive inflammatory ocular conditions
  • Superficial bacterial ocular infection
  • Chronic anterior uveities
  • Corneal injury from chemical, radiation or thermal burns
  • Penetration of foreign bodies

Pharmacology

  • Bactericidal activity of Tobramycin
  • Inhibition of normal protein synthesis in bacteria
  • Inhibition of protein synthesis due to action on ribosome
  • Inhibition of phospholipase A2 by Dexamethasone
  • Inhibition of chemo-tactic infiltration of neutrophils

Dosage & Administration

  • Eye Drops: 3-5 times per day
  • Increased dosage during initial 24-48 hours
  • Eye Ointment: 3-4 times per day
  • Pediatric Use: Safety and effectiveness not established below age 2

Interaction

  • No specific interaction studies
  • Interval of 10 minutes between successive applications with other topical ophthalmic medicines

Contraindications

  • Epithelial herpes simplex keratitis
  • Vaccinia and varicella
  • Mycobacterial infection of the eye
  • Hypersensitivity to any component of the medication

Side Effects

  • Hypersensitivity
  • Localized ocular toxicity
  • Elevation of intraocular pressure
  • Possible development of glaucoma
  • Optic nerve damage
  • Posterior sub capsular cataract formation
  • Delayed wound healing

Pregnancy & Lactation

  • Use during pregnancy if potential benefit justifies the potent risk to the fetus
  • Caution during nursing as systemic absorption in human milk is unknown

Precautions & Warnings

  • Consider possibility of fungal infections after long-term steroid dosing
  • Prolonged use may result in overgrowth of non-susceptible organisms
  • Cross-sensitivity to other aminoglycoside antibiotics
  • Discontinue use if hypersensitivity develops

Overdose Effects

  • Overdose through local administration not known
  • Specific measures to reduce resorption in case of accidental oral intake

Therapeutic Class

  • Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

  • Store at room temperature
  • Close the bottle immediately after use
  • Do not use for longer than one month after opening

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