Tomycin-D 0.1%+0.3% (Ophthalmic Solution)

5 ml drop: ৳ 150.00

Medicine Details

Category Details
Generic Dexamethasone tobramycin
Company Ibn sina pharmaceuticals ltd
Also available as
Tomycin d 01 03 eye ointment

Indications

  • Steroid responsive inflammatory ocular conditions
  • Chronic anterior uveities
  • Corneal injury from chemical radiation or thermal burns
  • Penetration of foreign bodies

Pharmacology

  • Bactericidal activity of Tobramycin
  • Inhibition of normal protein synthesis in susceptible bacteria
  • Inhibition of phospholipase A2 by Dexamethasone
  • Inhibition of chemo-tactic infiltration of neutrophils by Dexamethasone

Dosage & Administration

  • 1 drop into the conjunctival sac 3-5 times per day for Eye Drops
  • Apply a small amount into the conjunctival sac 3-4 times per day for Eye Ointment
  • Safety and effectiveness in pediatric patients below the age of 2 years have not been established for Pediatric Use

Interaction

  • No specific interaction studies performed with Tomycin-D eye drops
  • Allow 10 minutes interval between successive applications if concomitant therapy with other topical ophthalmic medicines

Contraindications

  • Epithelial herpes simplex keratitis
  • Vaccinia
  • Varicella
  • Mycobacterial infection of the eye
  • Hypersensitivity to any component of the medication

Side Effects

  • Hypersensitivity
  • Localized ocular toxicity
  • Elevation of intraocular pressure
  • Possible development of glaucoma
  • Infrequent optic nerve damage
  • Posterior sub capsular cataract formation
  • Delayed wound healing

Pregnancy & Lactation

  • No adequate and well controlled studies in pregnant women
  • Use during pregnancy only if potential benefit justifies the potent risk to the fetus
  • Not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Consider possibility of fungal infections of the cornea after long-term steroid dosing
  • Prolonged use may result in overgrowth of non-susceptible organisms, including fungi
  • If super infection occurs, appropriate therapy should be initiated
  • Cross-sensitivity to other aminoglycoside antibiotics may occur
  • Hypersensitivity development requires discontinuation and appropriate therapy

Overdose Effects

  • Overdose through local administration is not known
  • In case of accidental oral intake, specific measures to reduce resorption should be taken
  • No specific antidote

Therapeutic Class

  • Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

  • Store at room temperature
  • Close the bottle immediately after use
  • Do not use for longer than one month after opening the bottle

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