Stedex-T 0.1%+0.3% (Ophthalmic Solution)

5 ml drop: ৳ 150.45

Medicine Details

Indications

  • Steroid responsive inflammatory ocular conditions
  • Chronic anterior uveitis
  • Corneal injury from chemical, radiation or thermal burns
  • Penetration of foreign bodies
  • Combination with anti-infective component

Pharmacology

  • Bactericidal activity of Tobramycin
  • Inhibition of normal protein synthesis in bacteria
  • Inhibition of phospholipase A2 by Dexamethasone
  • Inhibition of chemo-tactic infiltration of neutrophils by Dexamethasone
  • Anti-inflammatory activity of Dexamethasone

Dosage & Administration

  • Eye Drops dosage
  • Eye Ointment application
  • Dosage adjustment during initial 24 to 48 hours
  • Pediatric Use safety

Interaction

  • No specific interaction studies conducted
  • Interval of 10 minutes between successive applications

Contraindications

  • Epithelial herpes simplex keratitis
  • Vaccinia and varicella
  • Mycobacterial infection of the eye
  • Hypersensitivity to any component

Side Effects

  • Hypersensitivity
  • Localized ocular toxicity
  • Elevation of intraocular pressure
  • Possible development of glaucoma
  • Optic nerve damage
  • Posterior sub capsular cataract formation
  • Delayed wound healing

Pregnancy & Lactation

  • Pregnancy - no adequate and well controlled studies
  • Use in pregnancy if potential benefit justifies the potent risk
  • Not known effects on nursing mothers

Precautions & Warnings

  • Possibility of fungal infections of the cornea
  • Risk of overgrowth of non-susceptible organisms
  • Cross-sensitivity to other aminoglycoside antibiotics

Overdose Effects

  • Overdose through local administration not known
  • Specific measures to reduce resorption in case of accidental oral intake
  • No specific antidote

Therapeutic Class

  • Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

  • Store at room temperature
  • Close the bottle immediately after use
  • Do not use for longer than one month after opening

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