Diflupred 0.05% (Ophthalmic Emulsion)
5 ml drop: ৳ 230.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Difluprednate |
| Company | General pharmaceuticals ltd |
Indications
- Treatment of inflammation and pain associated with ocular surgery
- Treatment of uveitis
- Treatment of pseudophakic cystoid macular edema
- Treatment of ocular surface diseases (e.g. blepharitis & corneal inflammation)
Pharmacology
- Inhibition of inflammatory response
- Delay or slow healing
- Inhibition of edema and fibrin deposition
- Inhibition of scar formation
- Induction of phospholipase A2 inhibitory proteins
- Control of biosynthesis of inflammatory mediators
Dosage and administration
- Instill 1 drop into the conjunctival sac of the affected eye 4 times daily
- Tapering dosage based on response
- Specific dosing regimens for different indications
Interaction
- Specific drug interaction studies not conducted
Contraindications
- Contraindicated in active viral diseases of the cornea and conjunctiva
- Contraindicated in mycobacterial infection of the eye
- Contraindicated in fungal diseases of ocular structures
Side effects
- Elevated intraocular pressure
- Visual acuity and field defects
- Cataract formation
- Secondary ocular infection
- Perforation of the globe
- Various ocular adverse reactions
Pregnancy and lactation
- Pregnancy Category C
- Potential embryotoxic and teratogenic effects in animal studies
- Caution advised during pregnancy and lactation
Precautions and warnings
- Prolonged use may result in glaucoma and cataract formation
- Caution required in patients with a history of herpes simplex
- Risk of fungal infections
- Proper handling and usage precautions
Use in special populations
- Safety profile in pediatric patients
- No significant differences in safety or effectiveness in geriatric patients
Overdose effects
- Overdosage unlikely to cause acute problems
- General guidance for accidental ingestion
Therapeutic class
- Ophthalmic steroid preparations
Storage conditions
- Room temperature storage
- Protection from light and freezing
- Guidance on shelf life after opening