Fixgut 10 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Apex pharmaceuticals ltd |
| Also available as |
Title
- Fixgut 10 mg Tablet
Categories
- Medicine
- Gastrointestinal Aid
- Nausea and Vomiting Relief
Description
- Fixgut 10 mg Tablet is a dopamine antagonist medication used to treat nausea and vomiting
- A gastroprokinetic agent that helps relieve dyspeptic symptoms and acute nausea and vomiting
DosageAndAdministration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults and children
Pharmacology
- Domperidone is a dopamine antagonist
- Blocks dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach
- Restores normal motility and tone of the upper gastrointestinal tract
Indications
- Treatment of dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease-induced nausea and vomiting
- Speeding barium transit in radiological studies
Interaction
- Antagonism with anticholinergic drugs
- Lower oral bioavailability with simultaneous administration of antacids and antisecretory drugs
- Metabolic pathway through CYP3A4
- Potential influence on drug absorption
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction, or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
SideEffects
- Rare transient intestinal cramps
- Rare extrapyramidal phenomena in young children and adults
- Potential increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
PregnancyAndLactation
- Use during the first trimester if justified by therapeutic benefit
- Excretion in breast milk
- Caution in nursing mothers
PrecautionsAndWarnings
- Use with caution in children due to potential extra-pyramidal reactions
- Caution in patients with hepatic impairment
UseInSpecialPopulations
- Use with caution in infants
- Caution in liver and kidney disorders
- Review for patients on prolonged therapy
OverdoseEffects
- Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
- Activated charcoal administration recommended
TherapeuticClass
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
- Motility stimulants/Dopamine antagonist
StorageConditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
ChemicalStructure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure
CommonQuestions
- Fixgut 10 mg Tablet usage
- Tips for using Fixgut 10 mg Tablet