Metholone 0.1% (Ophthalmic Suspension)

5 ml drop: ৳ 110.00

Medicine Details

Category Details
Generic Fluorometholone acetate
Company Kemiko pharmaceuticals ltd

Indications

  • Treatment of steroid responsive inflammation of the palpebral and bulbar conjunctiva
  • Treatment of inflammation of cornea and anterior segment of the globe

Pharmacology

  • Corticosteroid with anti-inflammatory action
  • Acts by inducing phospholipase A2 inhibitory proteins (lipocortins)
  • Controls biosynthesis of mediators of inflammation
  • Demonstrated lower propensity to increase intraocular pressure

Dosage & Administration

  • Bottle should be shaken before use
  • 1 to 2 drops instilled into the conjunctival sac two to four times daily
  • Dosage may be safely increased to 2 drops every hour in initial 24 to 48 hours
  • Use in Children: Safety and effectiveness not demonstrated in children under 2 years

Interaction

  • Specific drug interaction studies not conducted with Metholone ophthalmic suspension

Contraindications

  • Acute superficial Herpes simplex keratitis
  • Fungal diseases of ocular structures
  • Vaccinia, varicella, mycobacterial infection of the eye
  • Viral diseases of the cornea and conjunctiva
  • Tuberculosis of the eye
  • Hypersensitivity to the constituents of this medication

Side Effects

  • Elevation of intraocular pressure with possible development of glaucoma
  • Loss of visual acuity or defects in fields of vision
  • Eye irritation, ocular hyperaemia, eye pain
  • Visual disturbance, foreign body sensation, eyelid edema, blurred vision
  • Eye discharge, eye pruritus, eye swelling
  • Posterior subcapsular cataract formation
  • Ulcerative keratitis, ocular infection, punctate keratitis
  • Hypersensitivity, rash, delayed wound healing

Pregnancy & Lactation

  • Pregnancy Category B3
  • Use during pregnancy only if potential benefit justifies potential risk to the fetus
  • Unknown systemic absorption into breast milk
  • Potential for serious adverse reactions in nursing infants

Precautions & Warnings

  • Caution required in patients with a history of Herpes simplex keratitis
  • Corticosteroid eye drops should not be used for more than 10 days without supervision
  • May mask, activate or aggravate an eye infection
  • If no improvement seen, consider alternative treatment

Therapeutic Class

  • Ophthalmic Steroid preparations

Storage Conditions

  • Store in a dry place and away from light
  • Keep out of reach of children
  • Prevent contamination of the dropper tip and suspension
  • Do not use after 4 weeks of first opening

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