Refemoline 0.1%+0.025% (Ophthalmic Solution)

5 ml drop: ৳ 100.00

Medicine Details

Category Details
Generic Fluorometholone tetrahydrozoline
Company Reman drug laboratories ltd

Indications

  • Acute and chronic allergic non-infectious conjunctivitis
  • Keratitis with severe swelling
  • Non-infectious inflammation of the anterior segment of the eye
  • Post-operative irritative conditions after strabismus
  • Cataract surgery with supplementary antimicrobial therapy
  • Glaucoma surgery with supplementary antimicrobial therapy

Pharmacology

  • Fluorometholone induces phospholipase A2 inhibitory proteins
  • Tetrahydrozoline is an alpha agonist which constricts the conjunctival blood vessels

Dosage & Administration

  • Use in adult: Instill 1 drop into the conjunctival sac 2-3 times daily
  • Dose may be increased for severe and adult patient to 1 drop hourly for first one to two days
  • Use in children: Safety & effectiveness in children below 2 years of age have not been established

Interaction

  • Tetrahydrozoline may interact with antidepressant drugs inhibiting MAO Enzyme

Contraindications

  • Infectious conjunctivitis or keratitis
  • Injuries or ulcerous processes of the cornea
  • Glaucoma
  • Diseases associated with stromal damage of the cornea or sclera
  • Dry eyes

Side Effects

  • Mild burning sensation
  • Reversible increase in intraocular pressure
  • Reactive hyperemia
  • Cataract & corneal defects
  • Glaucoma
  • Systemic effects

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnancy or while breast-feeding
  • Use during pregnancy only if potential benefits justify potential risk to the fetus

Precautions & Warnings

  • Avoid prolonged use
  • Use after careful risk-benefit evaluation in patients with severe blood circulation diseases
  • Metabolic disturbances
  • Under treatment with MAOIs and other potentially hypertensive drugs
  • History of cataract
  • Herpes simplex infection
  • Rhinitis sicca

Overdose Effects

  • Almost no likelihood of overdose when used as directed
  • No information on overdosage with fluorometholone is available
  • Symptoms of acute overdosage with tetryzoline are CNS, cardiac and psychiatric disturbances
  • Mydriasis
  • Cyanosis
  • Fever

Therapeutic Class

  • Ophthalmic Steroid preparations

Storage Conditions

  • Keep out of the reach of children
  • Store in a cool, dry place away from heat and direct light
  • Do not use more than 4 weeks after opening

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