Loteflam 0.5% (Ophthalmic Suspension)
5 ml drop: ৳ 175.53
Medicine Details
| Category | Details |
|---|---|
| Generic | Loteprednol etabonate |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Steroid responsive inflammatory conditions
- Allergic conjunctivitis
- Acne rosacea
- Superficial punctate keratitis
- Herpes zoster keratitis
- Iritis
- Cyclitis
- Post-operative inflammation
Pharmacology
- Inhibition of inflammatory response
- Delay or slow healing
- Inhibition of edema
- Inhibition of leukocyte migration
- Inhibition of scar formation
- Induction of phospholipase A2 inhibitory proteins
Dosage & Administration
- Instill 1 drop into the conjunctival sac
- 4 times a day for steroid responsive ocular inflammation
- 2 times a day for inflammation after surgery
- Apply small amount 4 times daily for ointment
- Instill one to two drops 4 times daily for gel
- Not established for pediatric patients
- No overall differences in safety and effectiveness for geriatric use
Interaction
- No expected effect on the pharmacokinetics of systemically administered medicinal products
Contraindications
- Contraindicated in most viral diseases of the cornea and conjunctiva
- Contraindicated in mycobacterial infection of the eye
- Contraindicated in fungal diseases of ocular structures
- Contraindicated in individuals with known or suspected hypersensitivity
Side Effects
- Elevated intraocular pressure
- Optic nerve damage
- Visual acuity and field defects
- Cataract formation
- Ocular infection
- Globe perforation
- Abnormal vision/blurring
- Burning on instillation
- Dry eyes
- Photophobia
- Headache
- Rhinitis
- Pharyngitis
Pregnancy & Lactation
- Pregnancy Category C
- Reproductive toxicity in animals
- Unknown risk for humans
- Caution during nursing
Precautions & Warnings
- Re-evaluate if no improvement after two days
- Monitor intraocular pressure for use of 10 days or longer
- Consider fungus invasion in persistent corneal ulceration
- Advise to consult a physician if aggravated symptoms
- Not to wear contact lenses during therapy
Therapeutic Class
- Ophthalmic Steroid preparations
Storage Conditions
- Store at below 30 degree C
- Dry place protected from light
- Do not touch tube tip to any surface
- Not be used one month after first opening
- Protect from freezing