Lotrel 0.5% (Ophthalmic Suspension)
5 ml drop: ৳ 175.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Loteprednol etabonate |
| Company | Eskayef pharmaceuticals ltd |
Indications
- Steroid responsive inflammatory conditions
- Allergic conjunctivitis
- Acne rosacea
- Superficial punctate keratitis
- Herpes zoster keratitis
- Iritis
- Cyclitis
- Post-operative inflammation
- Pain following ocular surgery
Pharmacology
- Inhibition of inflammatory response
- Delayed healing
- Edema inhibition
- Fibrin deposition inhibition
- Capillary dilation inhibition
- Leukocyte migration inhibition
- Fibroblast proliferation inhibition
- Collagen deposition inhibition
- Scar formation inhibition
- Mechanism of action through corticosteroids
- Induction of phospholipase A 2 inhibitory proteins
- Control of biosynthesis of inflammation mediators
Dosage & Administration
- Instillation of drops into the conjunctival sac
- Frequency of administration
- Application of ointment into conjunctival sac
- Use in children
- Geriatric use
Interaction
- No expected effect on pharmacokinetics of systemically administered medicinal products
Contraindications
- Contraindicated in viral diseases of the cornea and conjunctiva
- Contraindicated in mycobacterial eye infection
- Contraindicated in fungal diseases of ocular structures
- Contraindicated in hypersensitivity to ingredients
- Contraindicated in hypersensitivity to corticosteroids
Side Effects
- Elevated intraocular pressure
- Optic nerve damage
- Visual acuity and field defects
- Posterior subcapsular cataract formation
- Secondary ocular infection
- Perforation of the globe
- Ocular adverse reactions
- Non-ocular adverse reactions
Pregnancy & Lactation
- Pregnancy Category C
- Reproductive toxicity in animal studies
- Use in pregnancy only if clearly necessary
- Caution in nursing women
Precautions & Warnings
- Re-evaluation if symptoms fail to improve
- Monitoring of intraocular pressure
- Consideration of fungus invasion in persistent corneal ulceration
- Consultation upon aggravation of redness or itching
- Advice against wearing contact lenses during therapy
Therapeutic Class
- Ophthalmic Steroid preparations
Storage Conditions
- Temperature and light protection
- Avoid touching tube tip to surface
- Expiry after opening
- Protection from freezing
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