Lotepred Plus 0.5%+0.3% (Ophthalmic Suspension)

5 ml drop: ৳ 200.00

Medicine Details

Category	Details
Generic	Loteprednol etabonate tobramycin
Company	Aristopharma ltd

Indications

Steroid-responsive inflammatory ocular conditions
Allergic conjunctivitis
Acne rosacea
Superficial punctate keratitis
Herpes zoster keratitis
Iritis
Cyclitis
Chronic anterior uveitis
Corneal injury from chemical, radiation or thermal burns
Post-operative inflammation following ocular surgery

Pharmacology

Loteprednol - corticosteroid
Induction of phospholipase A2 inhibitory proteins
Inhibition of prostaglandins and leukotrienes biosynthesis
Tobramycin - aminoglycoside
Bactericidal activity by inhibiting protein synthesis of bacteria

Dosage & Administration

Shake well before use. Apply one drop into the conjunctival sac of the affected eye(s) every four to six hours. During the initial 24 to 48 hours, the dosing may be increased, to every one to two hours.

Interaction

Loteprednol Etabonate is not detected in plasma following the topical administration, not expected to affect the pharmacokinetics of systemically administered medicinal products

Contraindications

Viral diseases of the cornea and conjunctiva, known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids

Side Effects

Increased intraocular pressure
Burning and stinging upon instillation
Vision disorders
Discharge
Itching
Lacrimation disorder
Photophobia
Corneal deposits
Ocular discomfort
Eyelid disorder
Non-ocular adverse events (headache)

Pregnancy & Lactation

Use in pregnancy: no adequate and well-controlled studies in pregnant women, potential benefit justifies the potential risk to the fetus
Use in lactation: caution when administered to a nursing mother

Precautions & Warnings

Ophthalmic use only
Monitoring intraocular pressure if used for 10 days or longer
Fungal infections of the cornea
Overgrowth of nonsusceptible organisms including fungi with prolonged use
Cross-sensitivity to other aminoglycoside antibiotics

Use in Special Populations

Safety and effectiveness in pediatric patients have not been established

Therapeutic Class

Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

Store at room temperature & protect from light. Do not touch dropper tip to any surface. It is desirable that the contents should not be used four weeks after first opening of the bottle. Protect from freezing