Predflam 1% (Ophthalmic Suspension)

5 ml drop: ৳ 100.30

Medicine Details

Category Details
Generic Prednisolone acetate
Company General pharmaceuticals ltd

Indications

  • Treatment of steroid-responsive inflammation of the palpebral and bulbar conjunctiva
  • Treatment of inflammation of the cornea and anterior segment of the globe

Pharmacology

  • Decreases inflammation by inhibition of migration of polymorphonuclear leukocytes
  • Reversal of increased capillary permeability
  • Suppresses the immune system by reducing the activity and production of the lymphocytes and eosinophils

Dosage & Administration

  • Adult: Instill one drop into the conjunctival sac two to four times daily
  • Paediatric: Safety and effectiveness in pediatric patients have not been established

Interaction

  • No significant drug interactions reported

Contraindications

  • Contraindicated in viral diseases of the cornea and conjunctiva
  • Contraindicated in known hypersensitivity to any of the ingredients or other corticosteroids

Side Effects

  • Elevation of intraocular pressure (IOP) with possible development of glaucoma
  • Infrequent optic nerve damage
  • Posterior subcapsular cataract formation
  • Delayed wound healing
  • Fungal and viral infections of the cornea may develop with long-term applications of steroid

Pregnancy & Lactation

  • Pregnancy category C
  • Should be used during pregnancy only if clearly needed
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Shake the bottle well before use
  • Prolonged use may result in damage to the optic nerve
  • Defects in vision may occur if used for longer periods
  • Routine monitoring of intraocular pressure is recommended for longer term use

Overdose Effects

  • One-time accidental overdose generally will not cause acute problems
  • Long-term overdose may show general side-effects
  • Sufficient water should be taken in case of an accidental overdose

Therapeutic Class

  • Glucocorticoids

Storage Conditions

  • Store in a cool, dry place
  • Protect from light
  • Keep out of the reach of children
  • Protect from freezing
  • Shake well before using

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