Loridon 5 mg/ml (Pediatric Drops)
15 ml drop: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Modern pharmaceuticals ltd |
| Also available as |
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- ChemoreceptorTrigger Zone (CTZ) blocking
- Gastroprokinetic action
- Weak penetration of blood-brain barrier
- Restores normal motility and tone of upper gastrointestinal tract
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults and children
Interaction
- Anticholinergic drugs antagonism
- Lowered oral bioavailability with antacids and antisecretory drugs
- Inhibition of CYP3A4 enzyme
- Potential influence on absorption of orally administered drugs
Contraindications
- Known hypersensitivity
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Use during first trimester if justified by therapeutic benefit
- No evidence of increase in risk of malformations in humans
- Excretion in breast milk
- Not recommended for nursing mothers
Precautions & Warnings
- Caution in children due to risk of extra-pyramidal reactions
- Caution in hepatic impairment
Use in Special Populations
- Use in infants with caution and under close medical supervision
- Caution in patients with hepatic impairment
- Caution in patients with severe renal insufficiency
Overdose Effects
- Symptoms may include drowsiness, disorientation, extrapyramidal reactions
- Recommendations for management in case of overdosage
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions about Loridon 5 mg/ml Pediatric Drop
- Used to treat nausea and vomiting
- Quick tips for usage