Ketosma 1 mg/5 ml (Syrup)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketotifen fumarate oral |
| Company | Leon pharmaceuticals ltd |
| Also available as |
Indications
- Prophylactic treatment of bronchial asthma
- Symptomatic treatment of allergic conditions including rhinitis and conjunctivitis
- Alleviating complications of itching, pain, and tenderness associated with neurofibroma
- Symptomatic treatment of allergy such as hayfever and urticaria
Pharmacology
Ketotifen has anti-allergic properties similar to sodium chromoglycate for the prophylactic treatment of asthma. It also acts as an antihistamine and possesses marked anti-anaphylactic properties. It exerts a sustained inhibitory effect on histamine reactions and prevents asthmatic attacks. Ketotifen has been found effective in reducing the number, severity, and duration of asthma attacks.
Dosage & Administration
Adults: 1 mg twice daily with food, may increase to 2 mg twice daily in severe cases. Children above 3 years: 1 mg twice daily with food. Elderly: Same as adult dose or as advised by the physician.
Interaction
Potentiates the effects of sedatives, hypnotics, antihistamines, and alcohols. A reversible fall in platelet count may occur in some patients receiving Ketotifen concomitantly with oral antidiabetic agents.
Contraindications
Avoid concomitant use with oral antidiabetic agents. No recommendations for use during pregnancy or breastfeeding.
Side Effects
Drowsiness, dry mouth, and slight dizziness may occur at the beginning of treatment but usually disappear after a few days.
Pregnancy & Lactation
Not recommended for use during pregnancy and lactation due to lack of evidence of teratogenic effects.
Precautions & Warnings
Continuation of previous treatment for a minimum of two weeks after starting Ketotifen is important to avoid exacerbation of asthma. Patients should be warned not to operate vehicles or machinery on the first day of treatment. Avoid alcoholic drinks. Potentiates the effects of sedatives, hypnotics, antihistamines, and alcohol.
Overdose Effects
Reported features of overdosage include confusion, drowsiness, headache, bradycardia, and respiratory depression. Gastric lavage or emesis for elimination of the drug is recommended, with general supportive treatment as needed.
Therapeutic Class
Cromoglycate and related drugs
Storage Conditions
Store in a cool and dry place, protect from light, keep out of the reach of children.
Chemical Structure
- Molecular Formula: C19H19NOS
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-649-ketotifen-fumarate-oral-chemical-structure-WOrxlxSmVByavydbYqzn.svg
Common Questions about Ketosma 1 mg/5 ml Syrup
- What is Ketosma 1 mg/5 ml Syrup?: An antihistamine medication and mast cell stabilizer used to treat allergic conditions such as conjunctivitis, asthma, and urticaria.
- What is Ketosma 1 mg/5 ml Syrup used for?: Indicated in bronchial asthma, rhinitis, conjunctivitis, hayfever, and urticaria.
- Pregnancy warnings: Asthafen 1mg tablet may be unsafe to use during pregnancy.
- Breast-feeding warnings: Unknown. Human and animal studies are not available. Please consult your doctor.
- Effect on kidney function: No data available. Please consult doctor before consuming the drug.
- Effect on liver function: No data available. Please consult doctor before consuming the drug.