Loval 10 mg (Tablet)
Unit Price: ৳ 2.01 (10 x 10: ৳ 201.00)
Strip Price: ৳ 20.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Jayson pharmaceuticals ltd |
| Also available as |
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors
- Gastroprokinetic action
- Restores normal motility
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis
- Regulates lower esophageal sphincter pressure
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults
- Usual recommended oral dose for children
- Rectal administration for adults and children
- Maximum dose for adults
- Maximum dose for children
- Maximum period of treatment
Interaction
- Antagonizes antidyspeptic effect of domperidone
- Lower oral bioavailability with antacids and antisecretory drugs
- Metabolic pathway through CYP3A4
- Inhibition of CYP3A4 by certain drugs
- Effect on absorption of orally administered drugs
- No influence on neuroleptics action
- Suppresses unwanted peripheral effects of dopaminergic agonists
Contraindications
- Known hypersensitivity to domperidone
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena in young children
- Increase in plasma prolactin level
- Hyperprolactinaemia effects
- Rare allergic reactions
Pregnancy & Lactation
- Use during first trimester justified by therapeutic benefit
- No evidence of increase in risk of malformations in humans
- Excretion in breast milk
- Unlikely harm to the newborn
- Not recommended for nursing mothers
Precautions & Warnings
- Increased risk of extra-pyramidal reactions in children
- Use with caution in hepatic impairment
Use in Special Populations
- Caution in infants
- Caution in liver disorders
- Caution in kidney disorders
Overdose Effects
- Symptoms of overdosage
- Recommendations for managing overdosage
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure Image
Common Questions about Loval 10 mg Tablet
- Common uses of Loval 10 mg Tablet
- Specific tips for using Loval 10 mg Tablet