Naphalon 0.005%+0.02% (Ophthalmic Solution)

Indications

• Acute and chronic non-infectious conjunctivitis
• Nonspecific conjunctival irritation
• Irrigation of the tear ducts

Pharmacology

• Astringent effect of zinc ions
• Tissue-sealing effect of zinc ions
• Antiseptic effect of zinc ions
• Vasoconstrictive effect of Naphazoline

Dosage & Administration

• Adult dosage: 1 drop in the conjunctival sac, three to 4 times per day
• Caution in children's dosage of vasoconstrictors

Interaction

• Avoid use with MAO-blockers
• Potential interaction with tricyclic antidepressants

Contraindications

• Hypersensitivity to zinc sulphate, Naphazoline, and other ingredients
• Contraindicated in patients with narrow-angle glaucoma
• Contraindicated in patients with dry eye or keratoconjunctivitis sicca Sjogren's syndrome
• Not suitable for use in infants

Side Effects

• Mydriasis
• Slight increase of intraocular pressure
• Transient burning sensation after instillation
• Reactive redness of the eye (rebound effect)
• Possible systemic cardiovascular effects in rare cases
• Nonspecific fatigue in some patients

Pregnancy & Lactation

• No controlled animal or pregnant women studies available
• Effects during lactation not investigated

Precautions & Warnings

• Avoid uncontrolled use over extended periods
• Discontinue treatment if no improvement after 2 days
• Discontinue therapy if ocular discomfort or visual disturbance occurs
• Caution in patients with predisposition to glaucoma, hypertension, cardiovascular diseases, pheochromocytoma, aneurysm, hyperglycemia, and hyperthyroidism

Therapeutic Class

• Ophthalmic Non-Steroid drugs

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