Motodon 10 mg (Tablet)

Unit Price: ৳ 1.50 (100's pack: ৳ 150.00)

Medicine Details

Category Details
Generic Domperidone maleate
Company Medimet pharmaceuticals ltd
Also available as
Motodon 10 mg tablet

Title

  • Motodon 10 mg Tablet

Categories

  • Medicine
  • Gastrointestinal
  • Nausea
  • Vomiting
  • Prokinetic

Description

  • Dopamine antagonist medication
  • Used to treat dyspeptic symptom complex
  • Treats acute nausea and vomiting
  • Beneficial in Parkinson's disease
  • Speeds barium transit in radiological studies
  • Acts on ChemoreceptorTrigger Zone and stomach
  • Restores normal motility and tone of upper gastrointestinal tract
  • Facilitates gastric emptying
  • Enhances antral and duodenal peristalsis

Dimensions

  • Tablet: 10 mg

Color Options

  • White

Functions

  • Relieves epigastric fullness
  • Reduces abdominal pain
  • Alleviates early satiety
  • Controls heartburn
  • Prevents regurgitation

Dosage & Administration

  • Oral dose for adults: 10-20 mg every 6-8 hours daily
  • Maximum daily dose: 80 mg
  • Rectal administration: 30-60 mg every 4-8 hours

Materials

  • Domperidone

Technical Specifications

  • Metabolized through CYP3A4
  • Gastro-kinetic effects
  • Inhibits dopamine receptors
  • Weak penetration across blood-brain barrier

Usability Features

  • Should be taken before meals
  • Recommended dosage for children based on body weight

Interaction

  • Contraindicated with anticholinergic drugs
  • Avoid simultaneous administration with antacids and antisecretory drugs

Contraindications

  • Hypersensitivity to the drug
  • Neonates
  • Gastrointestinal hemorrhage
  • Mechanical obstruction
  • Perforation
  • Prolactin releasing pituitary tumor

Side Effects

  • Transient intestinal cramps
  • Rare extrapyramidal phenomena
  • Possible increase in plasma prolactin level
  • Rare allergic reactions

Pregnancy & Lactation

  • Use during first trimester if justified by therapeutic benefit
  • Excreted in breast milk
  • Not recommended for nursing mothers unless benefits outweigh risks

Precautions & Warnings

  • Caution in children due to risk of extra-pyramidal reactions
  • Use with caution in hepatic impairment

Use in Special Populations

  • Caution in infants due to immature blood-brain barrier
  • Use with caution in liver disorders
  • Use with caution in severe renal insufficiency

Overdose Effects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions

Therapeutic Class

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

Storage Conditions

  • Store below 30°C
  • Protected from light & moisture
  • Keep out of children's reach

Chemical Structure

  • Molecular Formula: C22H24ClN5O2
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

Common Questions and Answers

  • Usage: Relieves nausea, vomiting, and indigestion
  • Tips:
    • Should be taken before meals as prescribed
    • May cause dizziness and sleepiness
    • Avoid alcohol consumption
    • Dry mouth may occur as a side effect
    • Consult doctor if certain symptoms persist
    • Do not take for longer than 7 days without consulting doctor

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