Mydrimide 0.5% (Ophthalmic Solution)

5 ml drop: ৳ 70.26

Medicine Details

Category Details
Generic Tropicamide
Company Reman drug laboratories ltd
Also available as
Mydrimide 1 eye drop

Indications

  • Dilates pupil for eye examinations
  • Used in cycloplegic refraction
  • Used in examination of the fundus of the eye
  • Used before and after eye surgery

Pharmacology

  • Induces mydriasis and cycloplegia
  • Paralyzes the parasympathetic system
  • Acts by blocking the action of the parasympathetic nervous system
  • Competes with acetylcholine for uptake at receptor sites

Dosage & Administration

  • Instill 1 or 2 drops for refraction, repeated in 5 minutes
  • Additional drop may be instilled to prolong mydriatic effect if patient not seen within 20-30 minutes
  • Instill 1 drop 15-20 minutes prior to examination of the fundus

Interaction

  • Atropine like substances
  • Tricyclic antidepressants
  • Numerous H1 antihistaminic substances
  • Anti-cholinergic agents
  • Anti-Parkinson drugs
  • Phenothiazines
  • Neuroleptic drugs capable of reinforcing the effect of Mydrimide

Contraindications

  • Narrow angle glaucoma
  • Hypersensitivity to any component of the product

Side Effects

  • Slight burning sensation after instillation into the eye
  • Psychotic episodes and behavioral changes in children
  • Cardio-respiratory collapse in children
  • Impairs performance and responsiveness while driving or operating machinery
  • Increase in intraocular pressure
  • Allergic reaction
  • Dryness of the mouth
  • Tachycardia
  • Headache

Pregnancy & Lactation

  • Pregnancy Category C
  • Administer to pregnant woman only if clearly needed
  • Caution in nursing women as excretion in human milk is not known

Precautions & Warnings

  • Consider administration of an antidote (miotic) after examination
  • Patient should compress tear duct with finger for 2-3 minutes after instillation to reduce excessive systemic absorption
  • Use with care in older patients

Overdose Effects

  • Red face
  • Accelerated pulse
  • Dry mouth
  • Reduced sweating and secretion
  • Increase in body temperature
  • Contact emergency doctor in case of accidental ingestion
  • Administration of miotic agent (antidote) if required

Therapeutic Class

  • Mydriatic and Cycloplegic agents

Storage Conditions

  • Store at room temperature
  • Protect from light
  • Desirable not to use more than one month after opening

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