Motigen 10 mg (Tablet)
Unit Price: ৳ 2.01 (100's pack: ৳ 200.61)
Medicine Details
Category | Details |
---|---|
Generic | Domperidone maleate |
Company | Novo healthcare and pharma ltd |
Also available as |
Title
- Motigen 10 mg Tablet
Categories
- Medicine
- Gastrointestinal
- Pharmacology
Description
- Dopamine antagonist medication
- Used to treat nausea and vomiting
- Blocks dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach
- Gastroprokinetic action
- Restores normal motility and tone of the upper gastrointestinal tract
DosageAndAdministration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults: 10-20 mg every 6-8 hours daily
- Maximum dose for adults: 80 mg daily
- Pediatric dose based on body weight
Indications
- Dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Interaction
- Contraindicated with anticholinergic drugs
- Main metabolic pathway is through CYP3A4
- Inhibition by azole antifungals, macrolide antibiotics, HIV protease inhibitors, nefazodone
- Potential effect on absorption of concomitantly orally administered drugs
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
SideEffects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Possible increase in plasma prolactin level
- Rare allergic reactions
PregnancyAndLactation
- Should only be used during the first trimester if justified by therapeutic benefit
- Excreted in breast milk
- Not recommended for nursing mothers
PrecautionsAndWarnings
- Caution in children due to risk of extra-pyramidal reactions
- Caution in patients with hepatic impairment
UseInSpecialPopulations
- Use in infants with caution and close medical supervision
- Caution in patients with liver and kidney disorders
OverdoseEffects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
TherapeuticClass
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
StorageConditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
ChemicalStructure
- Molecular Formula: C22H24ClN5O2
FAQ
- Used to treat nausea and vomiting
- Helps relieve nausea, vomiting, and indigestion
- Side effects include dizziness and sleepiness
- Avoid alcohol consumption
- Inform doctor for persistent side effects
- Do not take for longer than 7 days without consulting doctor