Tropidil Plus 0.8%+5% (Ophthalmic Solution)
5 ml drop: ৳ 80.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Tropicamide phenylephrine hydrochloride |
| Company | Popular pharmaceuticals ltd |
Therapeutic Purpose
- Inflammatory conditions of the uveal tract
- Temporary lowering of intraocular pressure in glaucoma
Diagnostic Purpose
- Retinal photography
- Refractive errors
- Fundus examination/photography
- Slit lamp examination
Pre-operative Use
Visualization of structures behind the iris, such as cataract extraction, vitrectomy, and retinal detachment surgery
Mode of Action
- Tropicamide binds to and blocks the receptors in the muscles of the eye
- Tropicamide acts by blocking the responses of the iris sphincter muscle to the iris and ciliary muscles to cholinergic stimulation
- Phenylephrine Hydrochloride is a selective alpha-1 agonist causing mydriasis without cycloplegia
- Phenylephrine tends to reduce intraocular lesion by vasoconstrictor action
Dosage & Administration
- Uveitis: 1-2 drops bid-qid or as required
- Diagnostic Purpose/Pre-operative Purpose: Instill 1-2 drops in the eye(s) 15-20 minutes before examination. If examination is not conducted within 20–30 minutes, an additional drop may be placed in the eye(s) to prolong the effect
Interaction
Tropicamide may interfere with the antihypertensive action of carbachol, pilocarpine, or ophthalmic cholinesterase inhibitors
Contraindications
- Hypersensitivity to any of the components and narrow angles or narrow angle glaucoma
- Low birth weight infants and some elderly adults with severe arteriosclerotic cardiovascular or cerebrovascular disease
- During intraocular operative procedures when the corneal epithelial barrier has been disturbed
Side Effects
- Elevated IOP (occasionally)
- Stinging
- Blurred vision
- Tachycardia
- Photophobia
- Headache
- Parasympathetic stimulation
- Allergic reactions
- Systemic effects include arrhythmias, hypertension, and coronary artery spasm
Pregnancy & Lactation
The safety of this medication during pregnancy or lactation has not been established
Precautions & Warnings
- Caution should be taken when administered with, or up to 21 days after administration of monoamine oxidase (MAO) inhibitors as exaggerated adrenergic effects may result
- Consideration of psychotic reactions and behavioral disturbances in patients hypersensitive to anticholinergic drugs
- Use with extreme caution in infants
Overdose Effects
Excessive use in children and in certain susceptible individuals may produce systemic toxic symptoms
Therapeutic Class
Preparations for Ophthalmic diagnosis
Storage Conditions
Keep out of the reach of children. Store in a cool, dry place, away from heat and direct light. Do not use more than 4 weeks after opening