Benozol 1% (Ophthalmic Suspension)

Indications

• Treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma

Pharmacology

• Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion

Dosage & Administration

• Shake well before use
• Insert 1 drop in the affected eye(s) three times daily
• May be used concomitantly with other topical ophthalmic products
• Pediatric use: One drop in the affected eye(s) 2 times daily in pediatric patients (4 weeks to 5 years age)
• Geriatric use: No overall differences in safety or effectiveness observed between elderly and younger patients

Interaction

• Rare instances of drug interactions with high-dose salicylate therapy
• Consider potential drug interactions in patients receiving Benozol

Contraindications

• Hypersensitivity to any component of this product

Side Effects

• Most frequently reported adverse events were blurred vision and bitter, sour, or unusual taste
• Other reported adverse events include allergic reactions, alopecia, chest pain, conjunctivitis, dizziness, dry mouth, and more

Pregnancy & Lactation

• Pregnancy Category C
• Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus

Precautions & Warnings

• Sulfonamide and systemic absorption
• Adverse reactions attributable to sulfonamides may occur
• Fatalities rarely occurred due to severe reactions to sulfonamides
• Sensitization may occur when a sulfonamide is re-administered

Overdose Effects

• Electrolyte imbalance, development of an acidosis state, and possible nervous system effects may occur

Therapeutic Class

• Drugs for miotics and glaucoma

Storage Conditions

• Store at room temperature & protect from light
• Do not touch dropper tip to any surface
• Desirable that the contents should not be used more than four weeks after first opening of the bottle
• Protect from freezing

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