Pilorine 2% (Ophthalmic Solution)

10 ml drop: ৳ 150.00

Medicine Details

Indications

  • Chronic open angle glaucoma
  • Acute or chronic narrow angle glaucoma
  • Suspected glaucoma
  • Ocular hypertension

Pharmacology

  • Stimulates cholinergic receptors
  • Produces contraction of iris sphincter muscle
  • Resulting in pupillary constriction (miosis)
  • Constriction of ciliary muscle resulting in increased accommodation
  • Reduction in intraocular pressure

Dosage & Administration

  • Instill 1 drop 2-4 times daily
  • Apply pressure on the tear duct for one minute after application

Interaction

  • Belladonna alkaloids or cyclopentolate may interfere with the miotic effects of pilocarpine
  • May have their own mydriatic effects dampened

Contraindications

  • Hypersensitivity to any ingredient including excipients
  • Conditions where pupillary constriction is undesirable (e.g. acute iritis)
  • Retinal detachment or predisposing conditions

Side Effects

  • Temporary blurred vision
  • Burning
  • Stinging
  • Redness
  • Watering of the eyes
  • Decrease in night vision
  • Eye irritation
  • Headache
  • Eye pain
  • Increased sweating
  • Muscle tremors
  • Nausea
  • Vomiting
  • Diarrhea
  • Watering of the mouth
  • Troubled breathing or wheezing

Pregnancy & Lactation

  • Safe use during pregnancy not established
  • Ophthalmic pilocarpine is systemically absorbed

Precautions & Warnings

  • Exercise caution during night driving or hazardous work in poor light
  • Regular intraocular pressure measurements recommended

Overdose Effects

  • Dilution with water and other fluids is the usual response to overdose

Therapeutic Class

  • Drugs affecting exocrine secretions

Storage Conditions

  • Store at room temperature
  • Protect from light
  • Contents should not be used more than 4 weeks after opening

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