Gemolol 0.5% (Ophthalmic Solution)
5 ml drop: ৳ 70.21
Medicine Details
| Category | Details |
|---|---|
| Generic | Timolol maleate |
| Company | General pharmaceuticals ltd |
Indications
- Treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma
Pharmacology
- Non-selective β-adrenergic receptor blocker
- Reduction of aqueous humor formation
- β-blockade causes lowering of blood pressure
Dosage & Administration
- Initial instillation of 1 drop of 0.25% solution bid into the affected eye(s)
- May increase to 1 drop of 0.5% solution bid if inadequate response
- Decrease to 1 drop once daily if controlled
- Do not exceed 1 drop bid of 0.5% solution
- 0.25% or 0.5% Gel-forming eye drops: Instill 1 drop into the affected eye(s) once daily
Interaction
- Potential interactions with beta-adrenergic blocking agents, calcium antagonists, catecholamine-depleting drugs, digitalis, quinidine, clonidine, injectable epinephrine
Contraindications
- Bronchial asthma
- Severe chronic obstructive pulmonary disease
- Sinus bradycardia
- Second or third degree atrioventricular block
- Overt cardiac failure
- Cardiogenic shock
- Hypersensitivity to any component of this product
Side Effects
- Burning and stinging sensation of the eyes
- Bradycardia
- Hypotension
- Arrhythmia and AV or SA nodal block
- CHF
- Pulmonary edema
- Raynaud's phenomenon
- Headache
- Dizziness
- Fatigue
- Asthenia
- Abdominal discomfort
- Nausea
- Constipation
- Hypoglycemia
Pregnancy & Lactation
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
- Detected in breast milk following oral and ophthalmic drug administration
- A decision should be made whether to discontinue nursing or discontinue the drug
Precautions & Warnings
- Patients with inadequate cardiac function, DM, myasthenia gravis, cerebrovascular insufficiency, history of atopy
- Avoid abrupt withdrawal
- May mask signs of hyperthyroidism and hypoglycemia
- Ophth soln should not be used as monotherapy for angle-closure glaucoma
- Renal and hepatic impairment
- Pregnancy and lactation
Overdose Effects
- Systemic effects similar to those seen with systemic beta-adrenergic blocking agents such as dizziness, headache, shortness of breath, bradycardia, bronchospasm, and cardiac arrest
Therapeutic Class
- Drugs for miotics and glaucoma
Storage Conditions
- Store between 15-30° C
- Avoid freezing and protect from light