Timocare 0.5% (Ophthalmic Solution)

5 ml drop: ৳ 80.00

Medicine Details

Category	Details
Generic	Timolol maleate
Company	Healthcare pharmaceuticals ltd

Indications

Treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma

Pharmacology

Non-selective β-adrenergic receptor blocker
Reduction of aqueous humour formation
Lowering of blood pressure

Dosage & Administration

0.25% or 0.5% eye drop solution
Gel-forming eye drops
Initial dose of 1 drop bid
Maximum dosage
Once daily dose for gel-forming eye drops

Interaction

Potential interaction with epinephrine
Interactions with beta-adrenergic blocking agents, calcium antagonists, catecholamine-depleting drugs, digitalis, quinidine, clonidine, injectable epinephrine

Contraindications

Bronchial asthma
Severe chronic obstructive pulmonary disease
Sinus bradycardia
Second or third degree atrioventricular block
Overt cardiac failure
Cardiogenic shock
Hypersensitivity to any component

Side Effects

Burning and stinging sensation of the eyes
Bradycardia
Hypotension
Arrhythmia and AV or SA nodal block
CHF
Pulmonary edema
Headache
Dizziness
Fatigue
Asthenia
Abdominal discomfort
Nausea
Constipation
Hypoglycemia

Pregnancy & Lactation

Use during pregnancy only if potential benefit justifies potential risk to fetus
Detection in breast milk
Serious adverse reactions in nursing infants

Precautions & Warnings

Inadequate cardiac function
Diabetes mellitus
Myasthenia gravis
Cerebrovascular insufficiency
History of atopy
Avoid abrupt withdrawal
Major surgery
Mask signs of hyperthyroidism and hypoglycemia
Not to be used as monotherapy for angle-closure glaucoma
Renal and hepatic impairment

Overdose Effects

Inadvertent overdosage resulting in systemic effects similar to systemic beta-adrenergic blocking agents

Therapeutic Class

Drugs for miotics and glaucoma

Storage Conditions

Store between 15-30°C
Avoid freezing
Protect from light

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