Glumol 0.5% (Ophthalmic Solution)
5 ml drop: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Timolol maleate |
| Company | Globe pharmaceuticals ltd |
Indications
- Treatment of elevated intraocular pressure
- Patients with ocular hypertension
- Patients with open-angle glaucoma
Pharmacology
- Non-selective β-adrenergic receptor blocker
- Reduction of aqueous humour formation
- Lowering of blood pressure
Dosage & Administration
- Initial dose of 0.25% solution bid
- Increase to 0.5% solution bid if inadequate response
- Decrease to 0.5% solution once daily if controlled
- Instill 1 drop of gel-forming eye drops once daily
Interaction
- Possible mydriasis with concomitant therapy with epinephrine
- Interactions with beta-adrenergic blocking agents
- Interactions with calcium antagonists
- Interactions with catecholamine-depleting drugs
- Interactions with digitalis
- Interactions with quinidine
- Interactions with clonidine
- Interactions with injectable epinephrine
Contraindications
- Bronchial asthma
- Severe chronic obstructive pulmonary disease
- Sinus bradycardia
- Second or third degree atrioventricular block
- Overt cardiac failure
- Cardiogenic shock
- Hypersensitivity to any component of the product
Side Effects
- Burning and stinging sensation of the eyes
- Bradycardia
- Hypotension
- Arrhythmia and AV or SA nodal block
- CHF
- Pulmonary oedema
- Raynaud's phenomenon
- Headache
- Dizziness
- Fatigue
- Asthenia
- Abdominal discomfort
- Nausea
- Constipation
- Hypoglycaemia
Pregnancy & Lactation
- Use during pregnancy if potential benefit justifies potential risk to fetus
- Drug detected in breast milk
- Potential for serious adverse reactions in nursing infants
Precautions & Warnings
- Patients with inadequate cardiac function
- Patients with diabetes mellitus
- Patients with myasthenia gravis
- Patients with cerebrovascular insufficiency
- Patients with history of atopy
- Avoid abrupt withdrawal
- May mask signs of hyperthyroidism and hypoglycaemia
- Not to be used as monotherapy for angle-closure glaucoma
- Patients with renal and hepatic impairment
- Pregnancy and lactation
Overdose Effects
- Systemic effects similar to systemic beta-adrenergic blocking agents
- Dizziness
- Headache
- Shortness of breath
- Bradycardia
- Bronchospasm
- Cardiac arrest
Therapeutic Class
- Drugs for miotics and glaucoma
Storage Conditions
- Store between 15-30° C
- Avoid freezing
- Protect from light
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