Xalacom 0.005%+0.5% (Ophthalmic Solution)
2.5 ml drop: ৳ 781.94
Medicine Details
| Category | Details |
|---|---|
| Generic | Latanoprost timolol |
| Company | Pfizer |
Title and Categories
- Xalacom
- Glaucoma Medication
- Eye Drop
- Ocular Hypertension Treatment
Active Ingredients
- Latanoprost
- Timolol Maleate
Functions
- Reduction of Intraocular Pressure (IOP)
- Increase Drainage of Aqueous Humour
- Block Beta-receptors
- Lower Aqueous Humour Formation
Indications
- Indicated for Open-Angle Glaucoma
- Indicated for Ocular Hypertension
- Insufficiently Responsive to β-blockers
- Insufficiently Responsive to Prostaglandins
- Insufficiently Responsive to Other IOP Lowering Agents
Dosage and Administration
- Adult/Elderly Dosage: One drop in affected eye(s) once daily
- Missed Dose: Continue with next dose as normal
- Not Recommended for Children
Interaction
- No Specific Interaction Studies with Xalacom
- Observation for Potential Additive Effects of β-blockade
- Concomitant Use of Two Topical β-adrenergic Blocking Agents Not Recommended
- Possible Effect on Pupil Size
- Potential Interaction with Antidiabetic Agents
Contraindications
- Known Hypersensitivity to Latanoprost
- Known Hypersensitivity to Timolol
- Known Hypersensitivity to Benzalkonium Chloride
- Reactive Airway Disease Including Bronchial Asthma
- History of Bronchial Asthma
- Severe Chronic Obstructive Pulmonary Disease
- Sinus Bradycardia
- Second or Third Degree Atrioventricular Block
- Overt Cardiac Failure
- Cardiogenic Shock
Side Effects
- Increased Iris Pigmentation
- Darkening, Thickening, and Lengthening of Eyelashes
- Eye Irritation (Stinging, Burning, Itching)
- Eye Hyperaemia
- Corneal Disorders
- Conjunctivitis
- Blepharitis
- Eye Pain
- Headache
- Skin Rash
Pregnancy and Lactation
- No Reproduction Toxicity Studies Conducted
- Use During Pregnancy Requires Justification of Benefit vs. Risk
- Passage of Latanoprost and Metabolites into Breast Milk
- Presence of Timolol Maleate in Human Milk
- Caution Required in Nursing Women
Precautions and Warnings
- Caution in Patients with Macular Edema
- Caution in Aphakic Patients
- Caution in Pseudophakic Patients with Torn Posterior Lens Capsule
- Caution in Patients with Known Risk Factors for Macular Edema
- Caution in Patients Subjected to Spontaneous Hypoglycemia
- Caution in Diabetic Patients Receiving Insulin or Oral Hypoglycemic Agents
- Caution for Patients Wearing Contact Lenses
- Caution for Patients Driving or Using Machines
Overdose Effects
- No Human Data Available on Overdosage with Xalacom
- Symptoms of Systemic Timolol Overdosage: Bradycardia, Hypotension, Bronchospasm, Cardiac Arrest
- If Overdose Occurs, Treatment Should be Symptomatic
Therapeutic Class
- Drugs for Miotics and Glaucoma
Storage Conditions
- Store at 2-8° C
- Opened Bottles may store below 25° C