Motiper 10 mg (Tablet)
Unit Price: ৳ 2.00 (50's pack: ৳ 100.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Mystic pharmaceuticals ltd |
| Also available as |
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Functional origin nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Chemoreceptor Trigger Zone (CTZ) blocking
- Gastroprokinetic action
- Gastrointestinal motility
- Blood-brain barrier penetration
- Gastric emptying facilitation
- Esophageal peristalsis enhancement
Dosage & Administration
- Recommended oral dose for adults and children
- Timing of administration
- Dosing in dyspeptic symptom
- Dosing in acute and sub-acute conditions
- Rectal administration
- Treatment period
Interaction
- Concomitant administration of anticholinergic drugs
- Effect on oral bioavailability
- Metabolic pathway through CYP3A4
- Examples of CYP3A4 inhibitors
- Influence on absorption of orally administered drugs
- Interactions with neuroleptics and dopaminergic agonists
Contraindications
- Known hypersensitivity
- Neonates
- Dangerous gastrointestinal stimulation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Teratogenic effects in animals
- Use during first trimester of pregnancy
- Excretion in breast milk
- Harmful effects to the newborn
- Effect on ability to drive and use machines
Precautions & Warnings
- Caution in children
- Risk of extra-pyramidal reactions
- Metabolism in liver
- Caution in hepatic impairment
Use in Special Populations
- Use in infants
- Blood-brain barrier penetration in infants
- Use in liver disorders
- Use in kidney disorders
- Dosing frequency reduction in renal insufficiency
- Regular review for patients on prolonged therapy
Overdose Effects
- Symptoms of overdosage
- Treatment options for overdose
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Temperature storage
- Protection from light and moisture
- Keeping out of children's reach
Chemical Structure
- Molecular Formula
- Chemical Structure Image
Common Questions about Motiper 10 mg Tablet
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