Nudon 10 mg (Tablet)
Unit Price: ৳ 2.25 (10 x 10: ৳ 225.00)
Strip Price: ৳ 22.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Novatek pharmaceuticals ltd |
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiotherapy-induced nausea and vomiting
- Drug therapy-induced nausea and vomiting
- Migraine-induced nausea and vomiting
- Speeding barium transit in radiological studies
Pharmacology
- Dopamine antagonist
- Gastroprokinetic action
- Blocks dopamine receptors
- Weak penetration across blood-brain barrier
- Restores normal motility
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
Dosage & Administration
- Taken 15-30 minutes before meals
- Usual recommended oral dose for adults and children
- Different doses for dyspeptic symptoms and acute/sub-acute conditions
- Rectal administration dosage for adults and children
- Maximum daily dose
- Maximum period of treatment
Interaction
- Antagonistic effect with anticholinergic drugs
- Lowering of oral bioavailability by antacids and antisecretory drugs
- Metabolic pathway through CYP3A4
- Inhibition of CYP3A4 by certain drugs
- Possible influence on absorption of concomitantly orally administered drugs
- Actions on neuroleptics and dopaminergic agonists
Contraindications
- Hypersensitivity to the drug
- Neonates
- Potential dangerous gastrointestinal stimulation scenarios
- Patients with prolactin-releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Hyperprolactinaemia
- Allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Use during the first trimester if justified by therapeutic benefit
- No evidence of increase in risk of malformations in humans
- Excretion in breast milk
- Lower concentrations in breast milk compared to plasma
- Caution for nursing mothers
Precautions & Warnings
- Increased risk of extra-pyramidal reactions in young children
- Caution in patients with hepatic impairment
Use in Special Populations
- Use in infants under close medical supervision
- Caution in liver disorders
- Impact of severe renal insufficiency on elimination half-life
Overdose Effects
- Symptoms of overdosage
- Recommendations for management
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Chemical Structure
- Molecular formula
- Chemical structure image
Common Questions
- Nudon 10 mg Tablet usage
- Quick tips for usage