Buprocaine 0.4% (Ophthalmic Solution)

10 ml drop: ৳ 100.30

Medicine Details

Indications

  • Used to temporarily numb the front surface of the eye for eye pressure measurement
  • Used to numb the eye for foreign body removal

Pharmacology

  • Local anaesthetic
  • Binds to sodium channels
  • Stabilizes neuronal membrane
  • Reduces permeability to sodium ions
  • Inhibits depolarization of neuronal membrane
  • Blocks initiation and conduction of nerve impulses

Dosage & Administration

  • 0.4% solution for short ophthalmic procedures
  • Instill 1 drop for tonometry after 60 sec
  • Additional drop after 90 sec interval for sufficient anaesthesia
  • Avoid inflamed, infected, or damaged tissues
  • Protect anaesthetised eye from dust and bacterial contamination
  • Reduce systemic absorption by compressing the lacrimal sac at the medial canthus

Side Effects

  • Hypersensitivity reactions
  • Transient stinging and blurring of vision
  • Excitation of CNS
  • Muscle twitching and tremors
  • Convulsions

Pregnancy & Lactation

  • Pregnancy Category C
  • Potential benefit justifies the potential risk to the foetus

Precautions & Warnings

  • Reduce systemic absorption by compressing the lacrimal sac
  • Avoid in heart block, epilepsy, impaired cardiac conduction, myasthenia gravis
  • Protect from dust and bacterial contamination
  • Cornea may be damaged by prolonged application
  • Do not drive until normal vision restored

Therapeutic Class

  • Ocular perioperative drugs

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