Supraphen plus 5%+1% (Ear Drop)

10 ml drop: ৳ 20.06

Medicine Details

Indications

  • Treatment of acute bacterial ear infections

Pharmacology

  • Contains Chloramphenicol which inhibits bacterial protein synthesis
  • Contains Lidocaine which acts as a local anesthetic

Dosage & Administration

  • Instill 2-3 drops into the ear bid-tid for Otic/Aural Otitis externa

Interaction

  • Decreases effects of iron and vitamin B12 in anaemic patients
  • Reduces efficacy of chloramphenicol when taken with phenobarbitone and rifampin
  • Impairs the action of oral contraceptives
  • Potentially fatal interactions with oral anticoagulants, oral hypoglycemic agents, and phenytoin
  • Contraindicated with drugs that depress bone marrow function

Contraindications

  • Hypersensitivity or toxic reaction to the drug
  • Perforated ear drum
  • Herpes simplex and other viral conditions of the eye or ear
  • Mycosis

Side Effects

  • Ototoxicity

Pregnancy & Lactation

  • Pregnancy Category C & B with potential benefits justifying use in pregnant women despite potential risks
  • Adverse effects shown in animal reproduction studies

Precautions & Warnings

  • Avoid prolonged use
  • Discontinue immediately if local hypersensitivity reactions occur

Therapeutic Class

  • Aural Anti-bacterial preparations

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