Antazol 0.05% (Nasal Drop)
Medicine Details
| Category | Details |
|---|---|
| Generic | Xylometazoline hydrochloride |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Nasal congestion in colds, rhinitis, sinusitis, headache
- Tubal block and serous otitis media associated with nasal congestion
Description
Sympathomimetic agent with marked alpha-adrenergic activity intended for use in the nose. Constricts nasal blood vessels, decongests the mucosa of the nose and neighboring regions of the pharynx. Enables easier breathing through the nose.
Pharmacology
Causes vasoconstriction of nasal blood vessels to resume nasal airflow. Selective agonist at alpha-2B-adrenoceptors. Decreases nasal resistance and increases nasal airflow. Provides relief from earache, sore throat, and nasal decongestion.
Dosage & Administration
- Adults: 0.1% - 2 or 3 drops in each nostril two to three times daily
- Children 6 to 12 years: 0.05% - 2 or 3 drops in each nostril two or three times daily
- Children under 6 years: 0.05% - 1 drop in each nostril two or three times daily
- Children 2-12 years old: 0.05% - 1 spray per nostril not more often than three times per day
- Adults and adolescents: 0.1% - 1 spray into each nostril, 1 to 3 times daily as needed. Do not exceed 3 applications daily into each nostril
Interaction
No drug interactions reported.
Contraindications
Contraindicated in patients with transsphenoidal hypophysectomy or surgery exposing the dura mater. Also contraindicated in patients hypersensitive to Xylometazoline. Each bottle for single-person use only. Not for use for more than seven consecutive days.
Side Effects
- Burning sensation in the nose and throat
- Local irritation
- Nausea and dryness of the nasal mucosa
Pregnancy & Lactation
Pregnancy category C. Not recommended during pregnancy. Use while breastfeeding only on doctor's instructions.
Precautions & Warnings
Adult nasal drops (0.1%) not for children below 12 years. Avoid prolonged use for chronic rhinitis to prevent rebound congestion and drug-induced rhinitis.
Therapeutic Class
Nasal Anti-histamine preparations
Storage Conditions
Protect from light. Do not use the bottle more than 28 days after opening for hygiene purposes