Omidon 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 40.00

Medicine Details

Category	Details
Generic	Domperidone maleate
Company	Incepta pharmaceuticals ltd
Also available as	Omidon d 10 mg tablet Omidon 10 mg tablet Omidon 5 mg pediatric drop

Title

Omidon 5 mg/5 ml Suspension

Description

Omidon 5 mg/5 ml Suspension is a dopamine antagonist medication which is used to treat nausea and vomiting. It helps relieve dyspeptic symptom complex, acute nausea and vomiting, and Parkinson's disease-induced nausea and vomiting. Domperidone, the active ingredient, restores normal motility and tone of the upper gastrointestinal tract, facilitates gastric emptying, enhances peristalsis, and regulates contraction of the pylorus. It should be taken before meals, as per the prescribed dosage and duration. Omidon 5 mg/5 ml Suspension may cause dizziness and sleepiness. It is not recommended for use in neonates and mothers who are breastfeeding.

Dimensions

5 mg/5 ml
10-20 mg tablet
10-20 ml suspension
0.4-0.8 ml pediatric drops

Color options

White suspension

Functions

Relieves dyspeptic symptoms
Treats acute nausea and vomiting
Restores normal gastrointestinal motility
Facilitates gastric emptying
Enhances peristalsis
Regulates contraction of the pylorus

Materials

Domperidone
Dopamine antagonists
Prokinetic drugs
Motility stimulants

Technical specifications

Molecular Formula: C22H24ClN5O2
Chemical Structure: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

Design elements

Suspension bottle
Labeled packaging

Usability features

Relieves dyspeptic symptoms
Treats acute nausea and vomiting
Safe for use in adults and children
Should be taken with caution in hepatic impairment and renal insufficiency

Dosage administration

Adults:
- 10-20 mg (1-2 tablet or 10-20 ml suspension), every 6-8 hours daily. Maximum dose: 80 mg daily
Children:
- Oral Dose:
  - 2-4 ml suspension/10 kg body weight or 0.4-0.8 ml pediatric drops/10 kg body weight, every 6-8 hours daily
- Rectal Dose:
  - 30 mg every 4-8 hours for adults
  - Maximum daily dose rectally in children: 30 mg for those weighing 10 to 25 kg

Interaction

Antagonizes:
- Anticholinergic drugs
Lower Oral Bioavailability with:
- Antacids
- Antisecretory drugs
Metabolic Pathway:
- CYP3A4
Inhibitors of CYP3A4:
- Azole antifungals
- Macrolide antibiotics
- HIV protease inhibitors
- Nefazodone
Action On:
- Neuroleptics
- Dopaminergic agonists (bromocriptine, L-dopa)

Contraindications

Not to be used in:
- Known hypersensitivity to domperidone
- Neonates
Avoid in:
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Patients with prolactin releasing pituitary tumor (prolactinoma)

Side effects

Transient intestinal cramps
Rare extrapyramidal phenomena
Hyperprolactinemia
Neuroendocrinological phenomena
Allergic reactions (rash and urticaria)

Pregnancy lactation

Pregnancy:
- Use during the first trimester if justified by therapeutic benefit
Lactation:
- Not recommended for nursing mothers unless the expected benefits outweigh potential risk

Precautions warnings

Caution in children for increased risk of extrapyramidal reactions
Caution in hepatic impairment

Special populations

Infants:
- Use with caution and under close medical supervision
- Possible occurrence of neurological side effects in infants under 1 year
Liver Disorders:
- Caution in hepatic impairment
Kidney Disorders:
- Reduced dosing frequency and adjusted dose in severe renal insufficiency