P-Don 10 mg (Tablet)
Unit Price: ৳ 1.50 (100's pack: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Pharmadesh laboratories ltd |
| Also available as |
Title
- Domperidone 10 mg Tablet
Categories
- Medicine
- Gastrointestinal
- Prokinetic
Description
Domperidone 10 mg Tablet is a medication used to treat dyspeptic symptom complex, acute nausea, and vomiting, and other related conditions. It is a dopamine antagonist affecting the gastrointestinal motility.
DosageForm
- Tablet
DosageStrength
- 10 mg
ColorOptions
- White
Indications
- Epigastric sense of fullness
- Abdominal distension
- Upper abdominal pain
- Eructation
- Flatulence
- Early satiety
- Nausea
- Vomiting
- Heartburn
- Non-ulcer dyspepsia
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Gastroprokinetic action
ModeOfAction
- Blocks dopamine receptors in the Chemoreceptor Trigger Zone
- Blocks dopamine receptors in the stomach
- Restores normal motility and tone of the upper gastrointestinal tract
DosageAndAdministration
- Should be taken 15-30 minutes before meals
- Usual oral dose for adults: 10-20 mg every 6-8 hours daily
- Usual oral dose for children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily
Interaction
- Concomitant administration of anticholinergic drugs may antagonize the antidyspeptic effect of domperidone
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
SideEffects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions
PregnancyAndLactation
- Should be used with caution during the first trimester of pregnancy
- Excreted in breast milk
- Not recommended for nursing mothers
PrecautionsAndWarnings
- Use with caution in children
- Use with caution in patients with hepatic impairment
SpecialPopulations
- Use with caution in infants
- Use with caution in patients with liver disorders
- Use with caution in patients with severe renal insufficiency
OverdoseEffects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
TherapeuticClass
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
StorageConditions
- Store below 30°C
- Protected from light and moisture
ChemicalStructure
- MolecularFormula: C22H24ClN5O2
- ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg
CommonQuestions
- Used to treat nausea and vomiting
- Helps relieve nausea, vomiting, and indigestion
- May cause dizziness and sleepiness
- Avoid consuming alcohol when taking the tablet