P-Don 5 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 27.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Pharmadesh laboratories ltd |
| Also available as |
Indications
- Dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Gastroprokinetic action
- motility of the gastrointestinal tract
- gastric emptying
- esophageal peristalsis
- lower esophageal sphincter pressure
Dosage & Administration
- Taken before meals
- Usual recommended oral dose
- Dose for adults and children
- Rectal administration
Interaction
- Antagonistic effects with anticholinergic drugs
- Lowered oral bioavailability with antacids and antisecretory drugs
- Metabolic pathway through CYP3A4
- Inhibition of CYP3A4 by certain drugs
- Influence on the absorption of concomitant orally administered drugs
Contraindications
- Known hypersensitivity
- Neonates
- Gastrointestinal stimulation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions
Pregnancy & Lactation
- Use during the first trimester of pregnancy with caution
- Excretion in breast milk
- Effects on ability to drive and use machines
Precautions & Warnings
- Increased risk of extra-pyramidal reactions in young children
- Use with caution in hepatic impairment patients
Use in Special Populations
- Use in infants with caution
- Use in liver disorders
- Use in kidney disorders
- Regular reviews for patients on prolonged therapy
Overdose Effects
- Symptoms of drowsiness and extrapyramidal reactions
- Administration of activated charcoal
- Use of anticholinergic and antihistamine drugs
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions about P-Don 5 mg/5 ml Suspension
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