Peri 10 mg (Tablet)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Hudson pharmaceuticals ltd |
| Also available as |
Product Title
- Peri 10 mg Tablet
Categories
- Medicine
- Digestive health
- Nausea and vomiting relief
- Gastrointestinal motility enhancer
Description
- Dopamine antagonist medication
- Used to treat dyspeptic symptoms, acute nausea and vomiting, Parkinson's disease, and speeding barium transit in radiological studies
- Gastroprokinetic action based on blocking dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach
- Restores normal motility and tone of the upper gastrointestinal tract
- Enhances antral and duodenal peristalsis
- Facilitates gastric emptying
Color Options
- None
Dosage Form
- Tablet
- Suspension
- Rectal suppositories
Dosage and Administration
- Adult dose: 10-20 mg every 6-8 hours daily
- Maximum adult dose: 80 mg daily
- Children's dose based on body weight
- Taken 15-30 minutes before meals and, if necessary, before retiring
Ingredients
- Domperidone (10 mg per tablet)
Packaging Size Options
- 20 tablets
- 30 ml suspension
Dimensions
- Tablet size: 8mm diameter
Material
- Active ingredient: Domperidone
- Packaging material: Plastic container, Aluminum foil
Technical Specifications
- Molecular Formula: C22H24ClN5O2
- Chemical Structure: See image
Usability Features
- Helps relieve nausea, vomiting, and indigestion
- Assists in gastrointestinal motility
- Should be taken before meals
Design Elements
- Chemical structure image on packaging
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Interaction
- Antagonized by anticholinergic drugs
- Decreased oral bioavailability with concomitant use of antacids and antisecretory drugs
- Metabolism through CYP3A4 pathway
- May influence absorption of concomitantly orally administered drugs
Contraindications
- Hypersensitivity to domperidone
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction, or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Potential increase in plasma prolactin level
- Possible neurological side-effects in infants
- Rare allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Use during first trimester if justified by therapeutic benefit
- No evidence of increased risk of malformations in humans
- Excreted in breast milk at lower concentrations than plasma
- Not recommended during nursing unless expected benefits outweigh potential risk
Precautions & Warnings
- Caution in children due to risk of extra-pyramidal reactions
- Caution in patients with hepatic impairment
Use in Special Populations
- Caution in infants due to immature blood-brain barrier
- Caution in patients with hepatic impairment
- Dosage adjustment and reduced dosing frequency in severe renal insufficiency
Overdose Effects
- Symptoms include drowsiness, disorientation, and extrapyramidal reactions
- Administration of activated charcoal and close observation recommended
- Anticholinergic or antiparkinson drugs may be helpful in controlling extrapyramidal reactions
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
Common Questions
- Used for treating nausea and vomiting
- Relieves nausea, vomiting, and indigestion
- Caution while driving or doing activities requiring mental focus
- Avoid alcohol consumption during medication
- Potential side effects include dry mouth, diarrhea, fever, and stomach pain