Cebuten 400 mg (Capsule)
Unit Price: ৳ 120.00 (2 x 7: ৳ 1,680.00)
Strip Price: ৳ 840.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftibuten dihydrate |
| Company | Renata limited |
Indications
- Acute Bacterial Exacerbations of Chronic Bronchitis
- Acute Bacterial Otitis Media
- Pharyngitis and Tonsillitis
Pharmacology
- Ceftibuten is a semi-synthetic Cephalosporin antibiotic
- Exerts bactericidal action by binding to essential target proteins of the bacterial cell wall
Dosage & Administration
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
Interaction
- Theophylline & Antacid do not alter the pharmacokinetic profile of Cebuten
- Ranitidine increases the Cmax & AUC of Cebuten
Contraindications
- Known allergy to the cephalosporin group of antibiotics
Side Effects
- Nausea
- Headache
- Diarrhea
- Dyspepsia
- Dizziness
- Abdominal pain
- Vomiting
Pregnancy & Lactation
- Pregnancy Category B
Precautions & Warnings
- Prolonged treatment may result in possible emergence and overgrowth of resistant organisms
- Careful observation of the patient is essential
- Dose may require adjustment in patients with varying degrees of renal insufficiency
- Prescribed with caution to individuals with a history of gastrointestinal disease
Use in Special Populations
- Renal Impairment: Dosing adjustments based on creatinine clearance (CrCl)
- Hepatic Impairment: No dose adjustment necessary
Therapeutic Class
- Third generation Cephalosporins
Reconstitution
- The small bottle contains purified water and large bottle contains granules
- Pour the purified water completely into large bottle
- Tighten the cap of large bottle and shake the bottle for at least one minute
- Use a measuring cup or dropper for reconstituted suspension
- Prepared suspension to be consumed within 14 days of preparation if kept in a refrigerator
- Shake the bottle well each time before use
Storage Conditions
- Store below 25°C, protected from light and moisture
- For Suspension: After reconstitution, the suspension may be used for 14 days while stored at 2° to 8°C
- Keep out of reach of children