Remadon 10 mg (Tablet)
Unit Price: ৳ 1.95 (100's pack: ৳ 195.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Reman drug laboratories ltd |
Title
- Remadon 10 mg Tablet
Categories
- Medicine
- Gastrointestinal Health
- Nausea Relief
- Vomiting Relief
- Digestive Aid
Description
- Dopamine antagonist medication
- Blocks dopamine receptors in Chemoreceptor Trigger Zone (CTZ) and stomach
- Gastroprokinetic action
- Restores normal motility and tone of the upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis and lower esophageal sphincter pressure
Color Options
- White
Dosage Form
- Tablet
- Suspension
- Paediatric Drops
- Rectal Suppositories
Dosage Instructions
- Taken 15-30 minutes before meals
- Usual recommended oral dose for adults: 10-20 mg every 6-8 hours
- Maximum dose for adults: 80 mg daily
- Recommended dosage for children based on body weight
Interaction
- Contraindicated with anticholinergic drugs
- Should not be given simultaneously with antacids and antisecretory drugs
- Metabolized through CYP3A4 pathway
- Inhibitors of CYP3A4 may increase plasma levels of domperidone
Contraindications
- Hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Should be used with caution during the first trimester of pregnancy
- Excreted in breast milk of lactating rats
- Not recommended for nursing mothers unless benefits outweigh risks
Precautions
- Use with caution in children due to increased risk of extrapyramidal reactions
- Use with caution in patients with hepatic impairment
Special Populations
- Use with caution in infants and under close medical supervision
- Use with caution in patients with liver or kidney disorders
Overdose Effects
- Symptoms include drowsiness, disorientation, extrapyramidal reactions
- Activated charcoal may be administered
Therapeutic Class
- Motility Stimulants
- Dopamine Antagonist
- Prokinetic Drugs
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Uses
- Treats nausea and vomiting
- Relieves indigestion
- Should be taken before meals
Usability Features
- Helps relieve nausea, vomiting, and indigestion
- May cause dizziness and sleepiness
Warnings
- Increased risk of extrapyramidal reactions in young children
- Highly metabolized in the liver
Infant Use
- Use with caution in infants due to immature blood-brain barrier and potential neurological side effects
Renal Impairment
- Dosing frequency may need to be adjusted in patients with severe renal insufficiency
- Patients on prolonged therapy should be regularly reviewed
Antidyspeptic Effect
- Treats dyspeptic symptom complex
Acute Nausea and Vomiting
- Treats acute nausea and vomiting of functional, organic, or infectious origin
- May be induced by radiotherapy or drug therapy
Parkinson's Disease
- Treats dopamine-agonist induced nausea and vomiting
Radiological Studies
- Speeds barium transit in follow-through radiological studies