Susten 60 mg (Tablet)
Unit Price: ৳ 50.00 (1 x 5: ৳ 250.00)
Strip Price: ৳ 250.00
Medicine Details
Category | Details |
---|---|
Generic | Dapoxetine hydrochloride |
Company | Square pharmaceuticals plc |
Also available as |
Indications
- Treatment of premature ejaculation in men 18 to 64 years of age
- Persistent or recurrent ejaculation with minimal sexual stimulation
- Marked personal distress or interpersonal difficulty
- Poor control over ejaculation
Pharmacology
- Inhibition of neuronal reuptake of serotonin
- Potentiation of neurotransmitter's action
- Rapid absorption with maximum plasma concentrations occurring approximately 1-2 hours after intake
- Biotransformational pathways: N-oxidation, N-demethylation, Naphthyl hydroxylation, Glucuronidation, Sulfation
- Rapid distribution with a mean steady state volume of distribution of 162 L
- Metabolites primarily eliminated in urine as conjugates
- Terminal half life of approximately 19 hours
Dosage & Administration
- Recommended starting dose for all patients is 30 mg
- Maximum recommended dosing frequency of once every 24 hours
- Increased dose to maximum recommended dose of 60 mg if effect of 30 mg is insufficient
- May be taken with or without food
- Not recommended for use in individuals below 18 years of age
- Caution in patients with mild or moderate renal impairment
- Contraindicated in patients with moderate and severe hepatic impairment
Interaction
- Concomitant administration with CNS active medicinal products
- Prescribed with caution in patients who use PDE5 inhibitors or alpha adrenergic receptor antagonists
- Caution when used in patients taking Warfarin chronically
- Avoid combining with alcohol
Contraindications
- Known hypersensitivity to Dapoxetine Hydrochloride
- Significant pathological cardiac conditions
- Concomitant treatment with MAOIs, thioridazine, serotonin reuptake inhibitors, or other medicinal/herbal products with serotonergic effects
Side Effects
- Nausea
- Dizziness
- Dry mouth
- Headache
- Diarrhea
- Insomnia
- Low rates of sexual dysfunction
Pregnancy & Lactation
- Not indicated for use by women
- Unknown excretion through human breast milk
Precautions & Warnings
- Avoid use in combination with recreational drugs
- May lead to serious reactions if combined with certain recreational drugs
- Possibly prodromal symptoms of syncope
- Caution in patients with history of documented or suspected orthostatic reaction
- Caution in patients taking other medicinal products known to affect platelet function or anticoagulants
- Prescribed with caution in patients who use PDE5 inhibitors or alpha adrenergic receptor antagonists
Overdose Effects
- No case of overdose reported
- Symptoms of overdose with SSRIs include serotonin-mediated adverse reactions
- No evidence of withdrawal syndrome
Therapeutic Class
- Drugs for Erectile Dysfunction
Storage Conditions
- Store below 30°C
- Protect from light and moisture
- Keep out of reach of children