Sandom 10 mg (Tablet)
Unit Price: ৳ 2.02 (10 x 10: ৳ 202.00)
Strip Price: ৳ 20.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Synovia pharma plc |
| Also available as |
Title
- Sandom 10 mg Tablet
Categories
- Medicine
- Gastrointestinal Health
Description
- Dopamine antagonist medication used to treat nausea and vomiting
Color Options
- N/A
Form
- Tablet
- Suspension
- Paediatric Drops
- Suppositories
Dosage Instructions
- Take 15-30 minutes before meals
- Maximum daily dose of 80 mg for adults
- Dosage for children based on body weight
- Rectal administration for adults and children
- Maximum treatment period of 12 weeks in acute nausea and vomiting
Ingredients
- Domperidone
Pharmacology
- Blocks dopamine receptors in CTZ and stomach
- Restores normal motility and tone of upper gastrointestinal tract
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis and lower esophageal sphincter pressure
Indications
- Dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Interaction
- Antagonized by anticholinergic drugs
- Lowered oral bioavailability with antacids and antisecretory drugs
- Metabolized via CYP3A4 pathway
- Potential influence on absorption of concomitantly orally administered drugs
Contraindications
- Known hypersensitivity
- Neonates
- Gastrointestinal stimulation might be dangerous
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Possible increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Use during first trimester if justified by therapeutic benefit
- Excreted in breast milk at low concentrations
- Nursing not recommended unless benefits outweigh potential risks
Precautions & Warnings
- Increased risk of extra-pyramidal reactions in young children
- Caution in patients with hepatic impairment
Use in Special Populations
- Caution in infants and under 1 year olds due to immature blood-brain barrier
- Caution in patients with hepatic impairment
- Reduced dosing frequency in severe renal insufficiency
Overdose Effects
- Symptoms include drowsiness, disorientation, and extrapyramidal reactions
- Recommendation of activated charcoal administration and close patient observation
Therapeutic Class
- Motility Stimulants
- Motility stimulants/Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions
- Used to treat nausea and vomiting
- Relieves indigestion
- May cause dizziness and sleepiness
- Avoid alcohol consumption
- Inform doctor about side effects or prolonged use