Sandom 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 28.18

Medicine Details

Category Details
Generic Domperidone maleate
Company Synovia pharma plc
Also available as
Sandom 10 mg tablet Sandom 5 mg pediatric drop

Title

  • Sandom 5 mg/5 ml Suspension

Categories

  • Medicine
  • Pharmaceutical

Description

  • Dopamine antagonist medication used to treat nausea and vomiting.

Dimensions

  • 5 mg/5 ml

Color Options

  • N/A

Form

  • Suspension

Dosage & Administration

  • Should be taken 15-30 minutes before meals
  • Usual recommended oral dose for adults: 10-20 mg, every 6-8 hours daily
  • Maximum adult dose: 80 mg daily
  • Usual recommended dose for children: 2-4 ml suspension/10 kg body weight, every 6-8 hours daily

Indications

  • Dyspeptic symptom complex
  • Acute nausea and vomiting
  • Parkinson's disease
  • Radiological studies

Pharmacology

  • Dopamine antagonist
  • Blocks dopamine receptors in CTZ and stomach
  • Restores normal motility of upper gastrointestinal tract
  • Facilitates gastric emptying
  • Enhances antral and duodenal peristalsis

Interaction

  • Concomitant administration of anticholinergic drugs may antagonize the effect of domperidone
  • Antacids and antisecretory drugs should not be given simultaneously with domperidone
  • Main metabolic pathway is through CYP3A4 enzyme
  • May interact with neuroleptics and dopaminergic agonists

Contraindications

  • Known hypersensitivity to the drug
  • Neonates
  • Gastrointestinal hemorrhage, mechanical obstruction or perforation
  • Prolactin releasing pituitary tumor

Side Effects

  • Transient intestinal cramps
  • Rare extrapyramidal phenomena
  • Possible increase in plasma prolactin level
  • Rare allergic reactions such as rash and urticaria

Pregnancy & Lactation

  • Should only be used during the first trimester if justified by therapeutic benefit
  • Excreted in breast milk but concentrations are 4 times lower than plasma
  • Not recommended for nursing mothers unless benefits outweigh risks

Precautions & Warnings

  • Use with caution in children due to risk of extrapyramidal reactions
  • Use with caution in patients with hepatic impairment

Use in Special Populations

  • Use in infants with caution and under close medical supervision
  • Use with caution in patients with liver or kidney disorders

Overdose Effects

  • Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
  • Administration of activated charcoal and close observation recommended

Therapeutic Class

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

Storage Conditions

  • Store below 30°C
  • Protected from light & moisture
  • Keep out of children's reach

Chemical Structure

  • Molecular Formula: C22H24ClN5O2

Common Questions

  • Used to treat nausea and vomiting
  • Helps relieve nausea, vomiting, and indigestion
  • May cause dizziness and sleepiness
  • Avoid consuming alcohol while taking
  • Inform doctor in case of watery diarrhea, fever, or persistent stomach pain

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