Doxoma 400 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Drug international ltd |
| Also available as |
Title
Doxoma
Categories
- Bronchodilator
- Methyl xanthine derivatives
Description
Doxoma is used to treat bronchial asthma, bronchospasm, chronic obstructive pulmonary disease (COPD), and pulmonary disease with spastic bronchial component. It selectively inhibits phosphodiesterase 4, relaxes bronchial smooth muscle, and has a better safety profile compared to Theophylline.
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Pharmacology
- Inhibits phosphodiesterase 4
- Relaxes bronchial smooth muscle
- Selective inhibition of adenosine A1 and A2 receptors
- Inhibits platelet activating factor (PAF)
- Reduces leukotriene production
Dosage and administration
- Elderly:
- 200 mg tablet two or three times daily
- Adults:
- 400 mg tablet two or three times daily
- Children:
- >12 years: 10 ml syrup or 200 mg tablet two or three times daily
- 6-12 years: 6-9 mg/kg body weight two times daily
Interactions
- Contraindicated with other xanthine preparations
- Caution with ephedrine or other sympathomimetic drugs
- May interact with erythromycin, TAO, lincomycin, clindamycin, allopurinol, cimetidine, influenza vaccine, propanolol, phenytoin, and other anticonvulsants
Contraindications
- Known hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- Lactation
Side effects
- Nausea
- Vomiting
- Epigastric pain
- Headache
- Tachycardia
- Insomnia
- Tachypnea
- Hyperglycemia
- Albuminuria
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Pregnancy and lactation
- Use during pregnancy should be carefully evaluated case by case
- Contraindicated during lactation
- No interference with ability to drive and use machines
Precautions and warnings
- Considerations for factors affecting hepatic clearance
- Caution in patients with cardiac disease, hypertension, elderly, severe hypoxemia, hyperthyroidism, chronic corpulmonale, congestive heart failure, liver disease, peptic ulcer, renal impairment
Overdose effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
- Symptomatic treatment of cardiovascular collapse in case of overdose
Therapeutic class
Bronchodilator, Methyl xanthine derivatives
Storage conditions
Keep in a dry place away from light and heat. Keep out of the reach of children. Use only on prescription of specialist physician.