Sydon 10 mg (Tablet)

Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)

Medicine Details

Category Details
Generic Domperidone maleate
Company Mst pharma

Title

  • Sydon 10 mg Tablet

Categories

  • Medication
  • Gastrointestinal Health
  • Nausea & Vomiting Relief
  • Prokinetic Drug
  • Dopamine Antagonist

Description

  • A medication used to treat dyspeptic symptom complex
  • Effective in managing acute nausea and vomiting
  • Beneficial for patients with Parkinson's disease
  • Used in radiological studies to speed barium transit

Dosage & Administration

  • Should be taken 15-30 minutes before meals
  • Advice to be taken before retiring for the day
  • Usual recommended dose for adults and children

Pharmacology

  • Dopamine antagonist that primarily blocks receptors in the Chemoreceptor Trigger Zone and stomach
  • Restores normal motility and tone of the upper gastrointestinal tract
  • Enhances antral and duodenal peristalsis
  • Facilitates gastric emptying

Indications

  • Relief of dyspeptic symptom complex
  • Treatment of acute nausea and vomiting
  • Use in Parkinson's disease
  • Speeding barium transit in radiological studies

Interaction

  • Antagonism of antidyspeptic effect with anticholinergic drugs
  • Oral bioavailability reduction with antacids and antisecretory drugs
  • Metabolic pathway through CYP3A4
  • Potential influence on absorption of concomitantly orally administered drugs

Contraindications

  • Hypersensitivity to the drug
  • Neonates
  • Gastrointestinal hemorrhage, mechanical obstruction, perforation
  • Prolactin releasing pituitary tumor (prolactinoma)

Side Effects

  • Rare side effects including transient intestinal cramps and extrapyramidal phenomena
  • Possible increase in plasma prolactin level leading to neuroendocrinological phenomena
  • Rare allergic reactions like rash and urticaria

Pregnancy & Lactation

  • Use only during the first trimester of pregnancy if justified by therapeutic benefit
  • No evidence of increase in risk of malformations in humans
  • Excretion in breast milk
  • Effects on ability to drive and use machines

Precautions & Warnings

  • Absolute caution in the case of children due to risk of extra-pyramidal reactions
  • Use with caution in patients with hepatic impairment

Use in Special Populations

  • Use in infants with great caution and under close medical supervision
  • Use with caution in patients with liver disorders
  • Impact on dosing frequency in patients with severe renal insufficiency

Overdose Effects

  • Symptoms including drowsiness, disorientation, and extrapyramidal reactions
  • Recommendations for administration of activated charcoal and close observation

Therapeutic Class

  • Motility Stimulants
  • Dopamine Antagonist
  • Prokinetic drugs

Storage Conditions

  • Store below 30°C
  • Protected from light & moisture
  • Keep out of children's reach

Chemical Structure

  • Molecular Formula: C22H24ClN5O2
  • Chemical Structure Image

Common Questions

  • Usage of Sydon 10 mg Tablet
  • Quick Tips for usage

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