Eprex 10000 IU (IV/SC Injection)
10000 IU pre-filled syringe: ৳ 7,300.00 (1 x 6: ৳ 43,800.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Cilag ag switzerland |
| Also available as |
Title
- Eprex Recombinant Human Erythropoietin
Categories
- Medicine
- Healthcare
- Pharmaceuticals
Description
Recombinant human erythropoietin (EPO), 165 amino acid sequence identical to human urinary EPO
Indications
- Treatment of anemia in Chronic Kidney Disease (CKD) patients on dialysis and not on dialysis
- Treatment of anemia in Zidovudine-treated HIV-infected patients
- Reduction of allogeneic RBC transfusions in patients undergoing elective, noncardiac, nonvascular surgery
- Prevention of anemia of prematurity in infants with specific birth weight and gestational age
Dosage
- Iron Stores Evaluation: Evaluate iron status before and during treatment
- CKD Patients: Monitor hemoglobin levels at least weekly until stable
- Dose Adjustment: Adjust dose based on hemoglobin response
- Administration Route:
- Intravenously
- Subcutaneously
- Pediatric Dosing: Specific starting dose for pediatric patients
Administration
- Preparation:
- Do not shake
- Protect syringe from light
- Inspect visually for particulate matter before administration
- Disposal: Discard unused portions of Erythropoietin alfa
Interaction
Simultaneous therapeutic administration with haematinic agents like ferrous sulphate may potentiate effect
Contraindications
- Uncontrolled hypertension
- Allergic reactions to Erythropoietin alfa
- Pure Red Cell Aplasia (PRCA)
Side Effects
- CKD Patients:
- Hypertension
- Arthralgia
- Muscle spasm
- Pyrexia
- Dizziness
- Zidovudine-treated HIV Patients:
- Pyrexia
- Cough
- Rash
- Injection site irritation
- Cancer Patients on Chemotherapy:
- Nausea
- Vomiting
- Myalgia
- Arthralgia
- Stomatitis
- Surgery Patients:
- Headache
- Injection site pain
- Chills
- Deep vein thrombosis
- Premature Infants: Fall in serum ferritin values
Pregnancy & Lactation
- Pregnancy: Use only if potential benefit outweighs potential risk to the fetus
- Lactation: Use with caution, considering benefit of breastfeeding and therapy to the woman
Overdose Effects
Can cause hemoglobin levels above desired level, leading to severe hypertension
Therapeutic Class
- Drugs for Haemolytic Hypoplastic Anemia
- Drugs for Renal Anemia
Storage Conditions
Store at 2°C to 8°C, protect from light, do not freeze or shake