Vave 10 mg (Tablet)

Unit Price: ৳ 4.00 (15 x 10: ৳ 600.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Aci limited
Also available as
Vave 5 mg suspension Vave 5 mg pediatric drop

Title

Vave 10 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

Vave 10 mg Tablet is a dopamine antagonist medication used to treat dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and in radiological studies. It works by blocking dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach, restoring normal gastrointestinal motility and enhancing gastric emptying.

Dimensions

  • Tablet Size: 10 mg
  • Packaging Size: 1 strip of 10 tablets, 1 bottle of 100 ml suspension
  • Storage Conditions: Store below 30°C, protect from light & moisture

Color Options

  • White

Functions

  • Relief of Symptoms:
    • Nausea
    • Vomiting
    • Indigestion
    • Abdominal Pain
  • Regulation of Gastrointestinal Motility: Enhancing gastric emptying, facilitating peristalsis

Dosage & Administration

  • Recommended Oral Dose for Adults: 10-20 mg every 6-8 hours daily
  • Maximum Daily Dose for Adults: 80 mg
  • Dosage Form:
    • Tablet
    • Suspension
  • Rectal Administration Dose: 30-60 mg every 4-8 hours for adults

Interaction

  • Antagonistic Effect: Concomitant administration of anticholinergic drugs
  • Inhibition of Oral Bioavailability:
    • Antacids
    • Antisecretory drugs
  • Metabolic Pathway: CYP3A4
  • Examples of CYP3A4 Inhibitors:
    • Azole antifungals
    • Macrolide antibiotics
    • HIV protease inhibitors

Contraindications

  • Hypersensitivity: Known hypersensitivity to Domperidone
  • Neonates: Contraindicated
  • Gastrointestinal Stimulation Risks:
    • Hemorrhage
    • Obstruction
    • Perforation
  • Prolactin-Releasing Pituitary Tumor: Contraindicated

Side Effects

  • Rare Side Effects:
    • Transient intestinal cramps
    • Extrapyramidal phenomena
  • Potential Neuroendocrinological Effects:
    • Galactorrhea
    • Gynecomastia
  • Other Reported Reactions:
    • Rash
    • Urticaria

Special Precautions

  • Children: Increased risk of extra-pyramidal reactions
  • Liver Disorders: Use with caution
  • Kidney Disorders:
    • Adjust dosing frequency in severe renal insufficiency

Overdose Effects

May include drowsiness, disorientation, and extrapyramidal reactions

Therapeutic Class

  • Motility Stimulants
  • Dopamine Antagonist
  • Prokinetic Drugs

Chemical Structure

  • Molecular Formula: C22H24ClN5O2
  • Structure Image: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

Pregnancy & Lactation

  • Pregnancy Use: Justified in first trimester if therapeutic benefit outweighs risk
  • Breastfeeding: Not recommended unless expected benefits outweigh potential risk

Common Questions

  • Use of Vave 10 mg Tablet: Treatment of nausea and vomiting
  • Quick Tips:
    • Take before meals as per prescribed dose
    • Avoid alcohol consumption
    • Inform doctor if persistent side effects occur

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