Vave 5 mg/ml (Pediatric Drops)
15 ml drop: ৳ 25.08
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Aci limited |
| Also available as |
Title
Domperidone 5 mg/ml Pediatric Drop
Categories
- Medicine
- Pediatric Drop
- Dopamine Antagonist
- Gastrointestinal Medication
- Prokinetic
- Motility Stimulant
Description
Domperidone is a dopamine antagonist used to treat dyspeptic symptoms, acute nausea and vomiting, and Parkinson's disease. It acts by blocking dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach, restoring normal motility and tone of the upper gastrointestinal tract.
Dimensions
N/A
Color Options
- Clear liquid
Functions
- Relieves dyspeptic symptoms
- Controls acute nausea and vomiting
- Restores normal gastrointestinal motility
Materials
- Domperidone
Technical Specifications
- Dose for Adults: 10-20 mg every 6-8 hours daily
- Maximum Adult Dose per Day: 80 mg
- Dose for Children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily
Design Elements
N/A
Usability Features
- Prevents regurgitation of gastric content
- Enhances antral and duodenal peristalsis
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Functional, organic, infectious, dietetic origin-induced nausea and vomiting
- Radiotherapy or drug-induced nausea and vomiting
- Speeding barium transit in follow-through radiological studies
Mode of Action
Blocks dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach
Dosage & Administration
- Dosage Form: Oral suspension
- Administration: 15-30 minutes before meals and if necessary before retiring
- Rectal Administration: 30-60 mg every 4-8 hours for adults
Interaction
- Antagonistic Interaction: Anticholinergic drugs
- Antisecretory Drugs Interaction: Avoid simultaneous administration
- Metabolic Pathway: Through CYP3A4
- Inhibitors:
- Azole antifungals
- Macrolide antibiotics
- HIV protease inhibitors
- Nefazodone
Contraindications
- Known hypersensitivity to domperidone
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Neuroendocrinological phenomena (e.g., galactorrhea, gynecomastia)
- Allergic reactions (rash, urticaria)
Pregnancy & Lactation
- Use during first trimester if justified by therapeutic benefit
- Excreted in breast milk
- Not recommended for nursing mothers unless benefits outweigh risks
Precautions & Warnings
- Use with caution in children
- Use with caution in patients with hepatic impairment
Use in Special Populations
- Infants - use with great caution and under close medical supervision
- Liver disorders - use with caution
- Kidney disorders - dosing may need adjustment in severe renal insufficiency
Overdose Effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
Therapeutic Class
Motility Stimulants/Dopamine Antagonist
Storage Conditions
Store below 30°C, protected from light & moisture
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg
Common Questions
- Question: What is Vave 5 mg/ml Drops used for?
- Answer: Vave 5 mg/ml Drops is a dopamine antagonist medication which is used to treat nausea and vomiting.
- Question: Quick Tips
- Answers:
- Helps relieve nausea, vomiting and indigestion
- Should be taken before meals as per the dose and duration prescribed by your doctor
- May cause dizziness and sleepiness
- Avoid consuming alcohol when taking Vave 5 mg/ml Drops as it may cause excessive drowsiness
- Dry mouth may occur as a side effect
- Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away
- Do not take Vave 5 mg/ml Drops for longer than 7 days without consulting your doctor