Brezofil 400 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treats bronchial asthma
- Treats bronchospasm
- Treats chronic obstructive pulmonary disease (COPD)
- Treats pulmonary disease with spastic bronchial component
Pharmacology
- Novel bronchodilator
- Selective inhibition of phosphodiesterase 4
- Relaxes bronchial smooth muscle
- Inhibition of platelet activating factor (PAF)
- Inhibition of leukotriene production
Dosage & Administration
- Elderly: 200 mg tablet two or three times daily
- Adults: 400 mg tablet two or three times daily or as prescribed by the physician
- Children >12 years: 10 ml syrup or 200 mg tablet two or three times daily
- Children 6-12 years: 6-9 mg/kg body weight two times daily
- Doxophylline SR tablet for required daily dose of 400 mg
- Dosage based on body weight
Interaction
- Not to be administered with other xanthine preparations
- Limit consumption of caffeine-containing beverages and food
- Caution with ephedrine or other sympathomimetic drugs
- Possible reduction in hepatic clearance with certain drugs
Contraindications
- Hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- During lactation
Side Effects
- Nausea
- Vomiting
- Epigastric pain
- Headache
- Irritability
- Insomnia
- Tachycardia
- Extrasystoles
- Tachypnea
- Hyperglycemia
- Albuminuria
- Severe cardiac arrhythmias
- Tonic-clonic seizure
- Potential for overdose
Pregnancy & Lactation
- Animal tests show no interference with prenatal growth
- Clinical evaluation needed for use during pregnancy
- Contraindicated during lactation
- No effect on ability to drive or use machines
Precautions & Warnings
- Factors reducing hepatic clearance may increase plasma levels
- Caution in patients with various comorbidities
- Monitoring blood levels recommended in certain cases
- Use caution in patients with cardiovascular diseases and hypertension
- No risk of addiction or dependence
Overdose Effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
- Symptomatic treatment for cardiovascular collapse
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
- Use only on prescription of specialist physician