Vomino 10 mg (Tablet)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Monicopharma ltd |
| Also available as |
Product Title
- Vomino 10 mg Tablet
Product Category
- Medicine
- Gastrointestinal
- Antiemetic
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in Chemoreceptor Trigger Zone (CTZ) and stomach
- Gastroprokinetic action
- Restores normal motility and tone of the upper gastrointestinal tract
- Facilitates gastric emptying
Dosage & Administration
- Taken 15-30 minutes before meals
- Adults: 10-20 mg every 6-8 hours daily
- Children: Dosage based on body weight
- Rectal administration for specific cases
Interaction
- Contraindicated with anticholinergic drugs
- Avoid simultaneous administration with antacids and antisecretory drugs
- Metabolized through CYP3A4 pathway
- Potential interaction with drugs that inhibit CYP3A4
Contraindications
- Known hypersensitivity to domperidone
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Rare transient intestinal cramps
- Rare extrapyramidal phenomena
- Possible increase in plasma prolactin level
- Rare allergic reactions like rash and urticaria
Pregnancy & Lactation
- Not recommended during the first trimester
- Excreted in breast milk but concentrations are lower than plasma
- Effects on ability to drive and use machines
Precautions & Warnings
- Caution in children due to risk of extra-pyramidal reactions
- Caution in patients with hepatic impairment
Use in Special Populations
- Caution in infants and close medical supervision
- Caution in patients with hepatic or renal disorders
Overdose Effects
- Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
- Recommendation for activated charcoal administration and close observation
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions
- Used for treating nausea and vomiting
- Quick tips for usage and potential side effects